DISCUSSION Periodontal disease, which is characterized by gingival attachment loss and bone resorption, is a family of diseases affecting the dental supporting tissues. The currently recognized key Gram negative periodontopathogens in the periodontal pocket could damage periodontal tissues and good knowledge of these as well as an adequate treatment could be helpful in treatment of periodontal disease.6 Mechanical therapy is usually the first mode of therapy recommended and is considered the gold standard till date. However, the temporary effect of subgingival scaling and root planing and its inability to eradicate all periodontal pathogens is explained by the unfavourable anatomy or dimensions of periodontal pockets.5 Local delivery of antimicrobial …show more content…
However, the improvements were highly statistically significant in group B as compared to group A. This marked reduction in the proportions of sites that bled on probing represents significant reduction in inflammation and possibly, bacterial load in these sites. This is in agreement to another study by Gonzales et al17 where in the mean percentage of bleeding sites decreased from 95% to 35% after 10 days and to 42% after 28 days of placement of CHX chip. Goodson et al.18 have shown that local delivery of antimicrobial drugs had a significant effect in reducing the red-complex bacteria in the periodontal pocket. The larger reduction in PBI observed in the present study is likely due to the anti-infective effect that the frequent applications of these chips had on the microbial flora with chlorhexidine and inflammatory response due to flurbiprofen. The CHX chips resulted in similar and even greater response compared to the FBP …show more content…
These results exceed those by Machtei et al in a study21 after 8 weeks when using repeated local application of FBP and CHX chips. The greater CAL gain in the present study might be associated with the greater intensity of the application of the chips which in turn results in higher local concentration of the drug that might be responsible for the greater effect. It has been demonstrated that PGE2 and TXB2 levels decreased and remained relatively constant from day 29 to day 50 with flurbiprofen administration in a study by Abramson et al.22 Similar results were confirmed by various authors20,21,23,24,25,26 where there were significant improvements in the values of CAL after administration of FBP and CHX chips. When the comparison was made between the groups, no statistically significant differences were seen in the values of PD and CAL at 1, 3 and 6 months in between the groups. This is in agreement with the study done by Machtei et
Periodontal disease cannot be completely cured, but it can be
If the dentist diagnoses any gum disease, our hygienists are trained to treat mild to advanced gum disease with deep cleaning using latest technology. We are able in many cases to prevent the need for gum surgery for severe cases. Our ultrasonic scalers use sound waves to remove plaque and calculus (hardened plaque) and provide a more gentle and effective treatment. The ultrasonic scaler gets down to the base of the pocket better, disinfecting the full mouth. We use Arestin® antibiotic treatment and soft-tissue lasers to eliminate remaining bacteria.
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The first action i would take, would be to ask for the schools lunch schedules and test if the food they are serving has a high percentage of fluoride which is the cause of developing mottled teeth. The next step would be to test the public water fountains and test for a high percentage of fluoride as well. Then if either of the two tested positive then i would work to change their dieting schedules then better purifying the water of fluoride. I will then gather information over the next few weeks to see if the number of students with mottled teeth would decrease.
Gum swelling can happen for different reasons. While it is something you'll have to see as fast as time grants, you won't need to run out for pharmaceutical remembering the ultimate objective to get the swelling to go down. There are truly different trademark cures you can use to treat and reduce swollen gums. About Gum Swelling In an indistinguishable route from other distinctive parts of your body, your gums will swell when endeavoring to fight off a sullying, affliction, or is by and large heartbreaking.
(Levitt, 2004, p. 182). His statistics are compelling, but the reasoning seems slightly irrelevant, as argued by Baumer and
This is why this source also proved a relevant secondary source for my research.
There is a plethora of studies over the years that have thoroughly
Liga, & Kellis, 2012, p. 2266). Both of these studies have not only shown the
To better understand the data found, I have organized the literature review into
Prior approval for the study was obtained from the local ethical committee. Patients with chronic generalized periodontitis [(moderate and severe) according to CDC working group, 2007 criteria]. Age ranging from 35-60 ( mean 45) years, should have at least 20 natural teeth, who have not received periodontal therapy, within preceding six months were included in this study. Tobacco in any form and alcoholics, any other systemic disease which can alter the course of periodontal disease, subjects should have pregnant, women on hormone replacement therapy or hormonal contraceptives, patients taking steroidal or non-steroidal anti-inflammatory drugs (previous 3 months) or antibiotics (previous 6 months), anti-inflammatory drugs and antibiotics in the previous six month and patients with aggressive periodontitis were excluded from this
Furthermore, the author declares that researchers report results in “… the July 21, Science.” This is inadequate credibility and does not provide sufficient reference. The author of this exposition provides credible sources, but this is not consistence throughout the
Therefore, this overturns the entire claim of the research question. This study also stated some contradictory findings when it came to
Therapeutic drug monitoring (TDM) is the clinical practice of measuring specific drugs at timed intervals in order to maintain a relatively constant concentration in a patient's bloodstream, thereby optimizing individual dosage regimens. It is not necessary to use therapeutic drug monitoring for all the of medications, and it is used mainly for monitoring drugs with some narrow therapeutic ranges, drugs with marked variability in pharmacokinetic, medications with target concentrations which are difficult to monitor, and drugs that are known to cause therapeutic and adverse effects. The process of therapeutic drug monitoring is based on the assumption that there is a specific relationship between dose and plasma or blood drug concentration, and between concentration and therapeutic effects. Therapeutic drug