The quantitative research that I will critique, is about the effectiveness of proton pump inhibitors (PPI) in reducing the risk of gastric injury in elderly patients who undergo an aspirin regimen. According to the study, over 50% of elderly patients who had taken either a Non-steroidal anti-inflammatory drugs (NSAID), or aspirin for less than 30 days presented some type of gastro intestinal (GI) lesion (cite). This very high number causes concern, since aspirin and NSAID’s are commonly used medications to treat, and prevent a variety of conditions. The study aims to answer two questions, the first is the risk of ulcers linked to the acute or chronic use of aspirin, and/or NSAIDs. The second question is the efficacy of anti-acid secretory treatments on these ulcers (cite). In this critique, I will be evaluating the data analysis, the findings, and the implications of the study. For the data analysis, each research question had a different data analysis approach. For the first question the researches used a statistical analysis performed by means of chi-square test, and Man-Whitney test. These two tests were used for the comparison of demographic characteristics, endoscopic diagnosis, and H. pylori …show more content…
For both questions the confidence intervals used were 95%. The researchers also used four tables and 1 figure with pertinent information to support the details of the study. In table number 1, characteristics of the demographic population and the endoscopic diagnoses were presented, and a higher prevalence of females were found to have gastrointestinal injuries due to aspirin or NSAID’s use. In figure 1, we can see that the risks of ulcers are diminished with the concomitantly use of aspirin or NSAID’s and a PPI medication. (cite). The results of the study are well presented and were made easy for other researchers to utilize the information in other