S. N. 2 Bromine Lab Report
You wish to substitute the bromine in the following molecules with a nucleophile. Explain whether the given molecule would react by S_N 1 or S_N 2 mechanism and explain why. 1-methyl-1-bromo-cyclohexane: S_N 1 mechanism because after Br leaves (leaving group departure) then it is a tertiary carbocation which is favored more in this type of mechanism. 1-bromopropane: This would react by S_N 2 mechanism because it is a primary alkyl halide, which undergo this type of mechanism. Also the nucleophile will be able to attack better because of its structure. 2-bromohexane: S_N 2 mechanism because there is less steric hindrance. Why does benzyl bromide react under both S_N 1 conditions and S_N 2 conditions? It can undergo each condition because in …show more content…
The better the leaving group, the faster the reaction making Br a better leaving group than Cl. Tertiary-butyl iodide reacts faster than tertiary-butyl bromide via S_N 2 mechanism because iodide is a better leaving group than bromide. True or False? True. 1-Chlorobutane (2.5 mL, d=0.886) in 20 mL of acetone is reacted with 90 mL of a 15 wt% solution of NaI in acetone. After work-up, you obtain 1.3 g of 1-iodobutane. Which is the limiting reagent? What is your % yield? Your instructor tells you to make 200 mL of a 1 wt% 〖AgNO〗_3 solution in ethanol, because the stock-room just ran out of the stuff. How would you do this? To promote the S_N 1 mechanism we used 〖AgNO〗_3 in a polar, protic solvent. True of False? Why? True. When the leaving group leaves, it typically makes a negative charge (anion) while the protic solvent is a cation. Electrons can then be donated forming a bond. Also, a strong nucleophile is not necessary in this mechanism. The rate of reaction for the S_N 2 mechanism is dependent on the concentration of both nucleophile and the electrophile. True or False? Justify your
Grignard Reaction Lab
397 Words | 2 PagesIn this experiment, the combined reactions are as follows. To start the experiment, the Grignard reagent, phenylmagnesium bromide, was formed by reacting bromobenzene with magnesium while using anhydrous diethyl ether as the solvent. Using anhydrous ether is crucial because if any water is present, the Grignard reagent will react with the water instead, which will ultimately terminate the reaction. Once formed, the Grignard reagent reacted with the benzophenone to form triphenyl magnesium bromide; this served as the Grignard adduct. From there, the Grignard adduct underwent an acid workup using aqueous 6M hydrochloric acid in order to form the product triphenylmethanol.
Mitochondria Lab Report
737 Words | 3 PagesDuring this experiment, mitochondria were isolated from 20.2 grams of cauliflower using extraction buffer, filtration through Miracloth, and centrifusion. Twelve samples containing various volumes of mitochondrial suspension, assay buffer, DCIP, sodium azide, and citric acid cycle intermediates were prepared to be read by a spectrophotometer. The inclusion of the dye DCIP allowed for the absorbance of the reactions between the mitochondrial suspension and the TCA cycle intermediates succinate, malonate, and oxalate to be measured, as DCIP turns from blue to colorless as the activity of succinate dehydrogenase increases. Experimental Findings Increasing the number of mitochondria in the reaction did increase the reduction of DCIP relative to the amount of mitochondrial suspension present.
Bromohexane Lab Report
1111 Words | 5 PagesThe goal of the experiment is to synthesize a bromohexane compound from 1-hexene and HBr(aq) under reflux conditions and use the silver nitrate and sodium iodide tests to determine if the product is a primary or secondary hydrocarbon. The heterogeneous reaction mixture contains 1-hexene, 48% HBr(aq), and tetrabutylammonium bromide and was heated to under reflux conditions. Heating under reflux means that the reaction mixture is heated at its boiling point so that the reaction can proceed at a faster rate. The attached reflux condenser allows volatile substances to return to the reaction flask so that no material is lost. Since alkenes are immiscible with concentrated HBr, tetrabutylammonium bromide is used as a phase-transfer catalyst.
Benefits Of Creatine Essay
396 Words | 2 PagesWhy creatine is your best friend Through the years there have been quite a few dietary supplements that promise natural muscle growth and performance enhancing effects. Of these, no preparations attracted such attention as creatine. Creatine is a naturally occurring substance that forms the body from the amino acids arginine, glycine and methionine, which are mainly found in the muscles. Creatine is also found in foods such as meat and fish.
Dropping Mentos Research Paper
181 Words | 1 PagesThe reaction is caused better because the mentos don't
Beta Galactosidase Lab Report
494 Words | 2 PagesEnzymes are proteins that significantly speed up the rate of chemical reactions that take place within cells. Some enzymes help to break large molecules into smaller pieces that are more easily absorbed by the body. Other enzymes help bind two molecules together to produce a new molecule. Enzymes are selective catalysts, meaning that each enzyme only speeds up a specific reaction. The molecules that an enzyme works with are called substrates.
Hydrolysis Of T-Butyl Chloride Lab Report
1766 Words | 8 PagesAbstract In this experiment, the reaction kinetics of the hydrolysis of t-butyl chloride, (CH3)3CCl, was studied. The experiment was to determine the rate constant of the reaction, as well as the effects of solvent composition on the rate of reaction. A 50/50 V/V isopropanol/water solvent mixture was prepared and 1cm3 of (CH3)3CCl was added. At specific instances, aliquots of the reaction mixture were withdrawn and quenched with acetone.
2-Bromobutane Lab Report
2033 Words | 9 PagesThe hydrogen removed must be anti to the leaving group. The mechanism of E2 reaction has only one steps, which is displacement of leaving group by removing hydrogen. The rate of the E1 elimination is based on substrate only, while it depends on both substrate and base in E2 elimination. E1 elimination is favored by weak base and ptotic solvents, while E2 is favored by strong base, high concentration of nucleophile and aprotic solvents. The major product of E2 elimination is the more substituent alkene, while the products of E1 elimination are trans-cis alkene and terminal
Substrate Concentration Lab Report
181 Words | 1 PagesHypothesis: Increasing substrate concentration will increase the initial reaction rate until it stops increasing and flattens out. Independent Variable: Substrate concentration Dependent Variable: The substrate itself, 1.0% Hydrogen Peroxide How Dependent Variable will be Measured: Hydrogen Peroxide will be used in every experiment, just with different test tubes. The amount of Hydrogen Peroxide in the mixing table is the amount that will be added to each test tube.
Lab Report Scaffold: Bromination Of Trans-Cinnamic Acid
904 Words | 4 PagesChem 51 LB Experiment 3 Report Scaffold: Bromination of Trans-Cinnamic Acid 1. The goal of this experiment was to perform a halogenation reaction through the addition of two bromides from pyridinium tribromide. This was accomplished by reacting trans-cinnamic acid with pyridinium tribromide. After the reaction took place, melting point analysis was conducted to find out the stereochemistry of the product, which could either be syn-addition, anti-addition, or syn + anti-addition. 2.
9-Fluorenone Lab Report
382 Words | 2 PagesThe purpose of this experiment was to learn about metal hydride reduction reactions. Therefore, the sodium borohydride reduction of the ketone, 9-fluorenone was performed to yield the secondary alcohol, 9-fluorenol. Reduction of an organic molecule usually corresponds to decreasing its oxygen content or increasing its hydrogen content. In order to achieve such a chemical change, sodium borohydride (NaBH4) is used as a reducing agent. There are other metal hydrides used in the reduction of carbonyl groups such as lithium aluminum hydride (LiAlH4).
Synthesis Of 3-Nitrochalcone Lab Report
391 Words | 2 PagesNext, the oxygen is protonated from the 3-nitrobenzaldehyde, which is then followed by an elimination reaction where this acts as a leaving group. The product is the trans-alkene present in the product. After the reaction was completed, purification of the product was conducted using semi-microscale recrystallization.
Pka Of Bromothymol Blue Lab Report
1221 Words | 5 PagesThis can be corroborated by the solvent-solvent extraction data detailed in Figure 4. Since organic-phase bromothymol blue (which rises to the top of the flask in a solvent-solvent extraction) is a neutral molecule, it must be the acidic form. Since the aqueous phase easily dissolves charged molecules, the deprotonated, negatively charged form of bromothymol blue is found here. Because the first peak on Figure 1 occurs at a lower pH, this must correspond to the organic-phase, protonated version of bromothymol
Nucleophilic Substitution Reactions Lab
1039 Words | 5 PagesIn nucleophilic substitution reactions, there are two possibilities, either Sn1 or Sn2. In this particular experiment, an Sn2 reaction
Diels Alder Reaction Lab
672 Words | 3 PagesSince the driving force of this reaction is the electron rich diene bonding to the electron poor dienophile as seen in Figure1 it is important to realize the effects that an electron withdrawing group would have on each compound. If an electron withdrawing group such as nitro- (NO2) is bonded to the diene it affects the electron density in a way that the diene no longer acts like an electron rich group, voiding the overall reaction as
More about S. N. 2 Bromine Lab Report
Grignard Reaction Lab
397 Words | 2 PagesMitochondria Lab Report
737 Words | 3 PagesBromohexane Lab Report
1111 Words | 5 PagesBenefits Of Creatine Essay
396 Words | 2 PagesDropping Mentos Research Paper
181 Words | 1 PagesBeta Galactosidase Lab Report
494 Words | 2 PagesHydrolysis Of T-Butyl Chloride Lab Report
1766 Words | 8 Pages2-Bromobutane Lab Report
2033 Words | 9 PagesSubstrate Concentration Lab Report
181 Words | 1 PagesLab Report Scaffold: Bromination Of Trans-Cinnamic Acid
904 Words | 4 Pages9-Fluorenone Lab Report
382 Words | 2 PagesSynthesis Of 3-Nitrochalcone Lab Report
391 Words | 2 PagesPka Of Bromothymol Blue Lab Report
1221 Words | 5 PagesNucleophilic Substitution Reactions Lab
1039 Words | 5 PagesDiels Alder Reaction Lab
672 Words | 3 Pages