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Abroma Augustum Essay

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Traditionally, Abroma augustum is having long history of medicinal use for treating various diseases. The purpose of the present investigation was to determine the phytochemical content and antioxidant potential of the leaves of Abroma augustum of Malaysian descent for first time. Antioxidant potential and polyphenolic compounds of A. augustum were evaluated by DPPH, FRAP assays and HPLC-PDA method respectively. Elemental analysis and Functional group analysis were done by an atomic absorption spectrophotometer (AAS) and Fourier Transform Infrared Spectrophotometer (FTIR) methods respectively. Qualitative analysis of each extract showed the presence of reducing sugars, alkaloids, tannins, phenols and flavonoids. Quantitative analysis of total …show more content…

It is widely distributed in Asia, South and East Africa and Australia [1]. The species is of Indo-Malaysian origin and it is found in peninsular Malaysia from Perak, Pahang, Selangor, and Kelantan States. A. augustum is a small shrub with a long history of medicinal use in Ayurveda system. It is highly useful in gynecological disorders. It regulates the menstrual flow and also used as abortifacient and anti-fertility agent. In India, it is used to treat dysmenorrhea and in Indonesia it is used in treating scabies. It is also used as anti- inflammatory, analgesic agent and in treating dermatitis [2]. The roots and bark of A. augustum are used to treat amenorrhoea, nervous dysmenorrhoea, sterility and other menstrual disorder. Leaves are useful in treating uterine disorders, diabetes, rheumatic pain, joints, and headache with sinusitis [3]. The root-bark is used as an emmenagogue and uterine tonic [3],[4]. Leaves and stem of A. augustum are used as a demulcent. Infusion of fresh leaves and stem in cold water is very efficacious in gonorrhea[5]. Medicinal plants are potential sources of phenols and flavonoids. Total phenols and flavonoids, as natural antioxidants and free radical scavengers.The role of free radical reactions in disease pathology is well established and is known to be involved in many acute and chronic disorders in human beings, such as arthritis, asthma, dementia,mongolism, carcinoma and parkinson’s disease. The free radicals in the human body are generated through aerobic respiration or from exogenous

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