In this lab, the oxidation of a secondary alcohol was performed and analyzed. An environmentally friendly reagent, sodium hypochlorite, was used to oxidize the alcohol, and an IR spectrum was obtained in order to identify the starting compound and final product. The starting compound could have been one of four alcohols, cyclopentanol, cyclohexanol, 3-heptanol, or 2-heptanol. Since these were the only four initial compounds, the ketone obtained at the end of the experiment could only be one of four products, cyclopentanone, cyclohexanone, 3-heptanone, or 2-heptanone. In order to retrieve one of these ketones, first 1.75g of unknown D was obtained. 1mL of Acetic acid was then added to Unknown D and the solution was stirred. Next, 15mL of sodium
In this lab, we tested 8 known ingredients to find what ingredients was in our unknown A and unknown B medications. We first tested the water solubility of our knowns and unknowns. We found that of the knowns, cornstarch and acetaminophen were the only ones not water soluble. The unknowns were also not water soluble. Th next test was the pH test. The unknowns were all basic except for the acetylsalicylic acid which was an acid and pseudoephedrine hydrochloride which was a neutral pH when tested. We tested our unknowns and found that both had a basic pH when tested. When we tested the ingredients for acetone solubility we found that most of the ingredients were acetone soluble except for acetaminophen, cornstarch, and sugar. For unknown A we
Acetaminophen is a molecule that is made of twenty atoms; its bonds consist of fourteen single bonds and four double bonds. Acetaminophen is also composed of clusters atoms with groups with names. First of all, part of an acetaminophen atom is a benzene ring. A benzene ring is a ring of six carbon atoms that are connected to each other by three double bonds and three single bonds and unusually all the bond are the same size. In addition, to make sure all the electrons in the outer valence are used the there are hydrogen atoms bonded to stabilize the carbon atoms. Second of all, one of the hydrogen atoms is substituted by a hydroxyl group. A hydroxyl is an oxygen atom bonded the carbon atom instead of a hydrogen and finally
First, two grams on an unknown white compound were given. The possible compounds the known could be were CaCO3, KNO3, NH4Cl, CaCl2, K2SO4, (NH4)2SO2, Ca(NO3)2, NaC2H2O2, K2CO3, MgCl2, Na2CO3, 0.1 M AgNO3, MgSO4, NaCl, 0.2 M BaCl2, KCl, NaSO4, Mg(s), HCl, HNO3, NaOH, HC2H3O2, H2SO4, and KOH.
NRC-04, a novel antimicrobial peptide derived from skin mucous secretions of flat fish winter flounder, shows a broad spectrum of antimicrobial activity. In order to understand the conformational change of NRC-04 in different types of membrane, our team did experiments on NRC-04 with negatively charged bacterial surface membrane mimetic micelles sodium dodecyl sulphate(SDS), zwitterionic eukaryotic middle membrane mimetic micelles dodecylphosphocholine(DPC), gram-negative bacteria outer membrane mimetic micelles Lipopolysaccharide(LPS) and bacterial inner membrane mimetic micelles 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol(POPG). Fluorescence test shows that the C-terminus tryptophan residue of NRC-04 interacts with the hydrophobic
The purpose of this experiment was to understand the pharmacokinetics of the drug acetaminophen within the body, specifically focusing on its partition coefficient, drug protein interaction and its bioavailability through various form of administration. The bioavailability of the drug was determined to be 100% for IV because the drug is injected directly into the systemic circulation in its active form and this is also visible on Figure 4, where the initial concentration of drug is much higher than in PO and IP. For PO and IP administration, the bioavailability was determined to be 72.6% and 39.1%, respectively. This makes sense because both of these type of administration involve the first-pass effect where a portion of the drug is metabolized by peripheral organs, especially the liver in this case, and therefore the amount of active drug reaching the circulation is less. PO administration, however has a much higher content reaching the circulation than IP, because the IP route involves passing through the whole gastrointestinal tract before being absorbed in the liver while the IP route injects the drug into the
Pediatric dosing for Acetaminophen for child < 60 kg is 10 to 15 mg/kg/dose orally every 4-6 hours. A maximum dose of 75 mg/kg/day in infants.
This was due to the stronger intermolecular forces between acetaminophen (hydrogen bonding from both the amide and phenol) and the solid stationary phase compared to the weaker intermolecular forces between acetylsalicylic acid (hydrogen bonding from the carboxylic acid) and the solid stationary phase. This resulted in faster desorption and slower resorption of acetaminophen compared to acetylsalicylic acid.
Acetaminophen is a very common medicine found in prescription and over-the-counter medications, used for the treatment of low fever and pain. It is the active ingredient in Tylenol. It is also called Acetaminophen and available in doses for infants, children, and adults.
In this diagram we can see that acetaminophen consists of a benzene ring core, with hydroxyl and amide functional groups in proxy.
Aspirin, Acetaminophen, an Ibuprofen have been around for centuries. They are mainly used to help the sickness of people, which may be minor or major. Acetylsalicylic Acid is another common name Aspirin maybe called. Aspirin treats minor aches, fever, and swelling. Aspirin has also been known to reduce the risk of a heart attack. Aspirins can be used in tablets, capsules, and caplets. Aspirin has also been known to be used in a powdered form. Aspirin has the chemical formula of C9H8O4. Aspirin was one of the first common drugs that people used the most. 35,000 metric tons of Aspirin are produced annually, which is about 100 billion tablets a year. Felix Hoffman invented Aspirin. Hoffman received a U.S patent as an inventor. Felix was born on
The unknown acid molarity will be determining by titration method. Titration is a process depends on concentration of known solution to another solution until the solute in the another solution completely react. Standard solution is the solution of known concentration that used in titration. In this experiment, NaOH was the titrant (base) however, the two analyte which used were HCl and H2SO4.
Treatment of fever in children is of greatest concern to parents. For the treatment of high temperatures (febrile illness) in children with the use of antipyretic drugs such as acetaminophen (panadol) and ibuprofen is widely available and widespread use among parents buying for their children.
molecules produced per unit time). In order to do so, enzymes bind temporarily to one or more reactants, lowering the amount of activation energy needed and thus speed up the reaction. Most of the cells use an enzyme called catalase to reduce the amount of hydrogen peroxide, a toxic substance that could accumulate as a result of normal cell activity. The purpose of this experiment was to observe the effects that enzyme concentration and copper (II) sulphate would have on the rate of reaction. This experiment was divided into two parts: Part A and Part B. In Part A, students would observe the effects of enzyme concentration on the rate of reaction. They were required to make six solutions with different concentration of catalase, the speed of
After reading over the information provided it is clear that ET and the physician have a right to be concerned. It appears as though EF relied on medication a little too much. As a result, it’s likely that she’s suffering from liver disease, which can be caused by an overdose in medications.