Advantages And Disadvantages Of Platelet Collection

Platelet collection methods

Introduction;

Platelet transfusion is given to patient with severe thrombocytopenia associated with failure of platelet production . the commonest indications arise in the treatment of acute leukemia and other neoplastic conditions involving the bone marrow and the depression of hematopoiesis by infections, drugs or unknown causes . there are two method of platelet collection either by whole blood donation or by plateletpheresis.

Methods and materials ; Preparation of PRP : PRP is obtained from a whole blood donation. A 450 ml venous blood draw will produce about 60 ml of PRP depending on the platelet count of a donor , the equipment and the method used . Addition of an anticoagulant to the blood, such as citrate dextrose A to prevent activation of platelet before its use. PRP is prepared by a process known as differential centrifugation. Apply a

(2)

Advantages of platelet aphereisis are exposure of the recipient to single donor rather than multiple donors and the ability to match donor and recipient characteristics such as HLA type. Cytomegalovirus (CMV) status , and blood type for certain recipients . (2)

Disadvantages of plateletpheresis are it is a more expensive technique and it is not without risk to the donor (3).it is also time consuming whole blood donations take 15 min and the whole appointment one hour while the platelet donation takes about 45 min and the whole appointment takes one and half hour . (5)

Discussion