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Diabetes Investigatory Project

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Effect of Aloe vera pulp extract (ALPE) on blood glucose levels in streptozocin induced diabetes in rats Vinoth Kumar A K, Alwar M C, Manjunatha C, Rohith V, Isabella Topno

ABSTRACT
Background
Diabetes is a metabolic syndrome characterized by hyperglycemia with various symptoms. Anti-diabetic drugs already available in market are producing various side effects like hypoglycemia, flatulence. Hence there is a need for new drugs with lesser side effects and high efficacy in reducing blood glucose levels. Materials and Methods: Albino rats were divided into six groups of six animals each. In five groups diabetes was induced by using streptozotocin (65 mg/kg i.p.). Group I – Normal control; Group II - Diabetic control; Group III – Diabetic + ALPE (150mg/kg); Group IV – Diabetic + ALPE (300mg/kg); Group V – …show more content…

The currently used hypoglycaemic drugs in the treatment of diabetes are not completely effective and are associated with inadequate control and adverse effects both in the short and long term. Several herbs have been tried in various studies with the aim to prevent or delay type 2 diabetes. Therefore there is a need to continue the search for more effective and safer drugs for the treatment of diabetes. Aloe vera (L) (synonym A. barbadensis Miller) (tamil- Southakathalai), ( Hindi: Ghikanvar ), (urdu name ghigwar) is a cactus like plant with green, dagger shaped leaves that are fleshy filled with a clear gel. The name was derived from Arabic “aloeh” meaning bitter, because of the bitter liquid found in the leaves.it is also known as “lily of the desert”, the plant of immortality and the medicine plant with qualities to serve as alternative

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