Alzheimer's Case Study
AD progression & diagnosis The progression of Alzheimer's can be described through several main cognitive stages starting at no cognitive decline through too mild to moderate before progressing to a more severe form of the disease. The pathological process associated with AD occurs roughly 20-25 years before symptoms appear (Mullane & Williams 2013). When symptoms become predominant Alzheimer’s can be diagnosed through a standardized scale (Mini-Mental State Exam) or questionnaire (Functional Activities Questionnaire) which is used to assess cognition (Desai & Grossberg 2005). Increasingly neuroimaging such as CT, MRI or PET scans are being suggested and used as a means to screen and diagnose for Alzheimer’s (Avila 2006; Borson et al. 2013). …show more content…
There are many different theories in relation to the pathology of AD; the most common include the role in which Amyloid-β proteins play, the effect of Tau protein aggregations along with synaptic dysfunction, especially the effect the loss of cholinergic neurons have and increasingly the role genetic factors seem to play. Amyloid cascade hypothesis The amyloid hypothesis was first proposed by John A. Hardy and Gerald A. Higgins in 1992 (Hardy & Higgins 1992) and has been the most popular theory to date as over the past decade the majority of research has focused on this pathway. To date amyloidal plaques are used as one of the two main hallmarks in identifying AD; the theory itself focuses on the production and altered clearance of amyloid; as it is hypothesised that the AβP molecule initiates the pathological cascade associated with AD (Hardy & Higgins …show more content…
2005) . Tau proteins are phosphorylated by two different types of kinases; which in turn regulate the binding of tau to microtubules and a genetic mutation in FAD (familiar AD) associated genes such as PS-1 can alter the function the allows for phosphorylation of tau proteins (Avila 2006). The formation of PHF-taus is thought to play a role in neurodegeneration as it’s believed to act as a neurotoxin. The increase and site of localisation of NFTs has been found to correlate with the level or stage of dementia a patient is experiencing; and consequently has been suggested to play a major role in the associated pathophysiology of AD (Avila 2006; Lee et al.
Unit 2 Dementia Research Paper
105 Words | 1 PagesDementia is a serious disorder caused by a variety of brain illnesses which affects a person memory .There are three symptoms stages which are early,middle,and late stages. A Person with dementia lose the ability to think well enough to do everyday activities or solve problems. It is also difficult for a person with dementia to interact with others which makes this disease overwhelming for the families of the Patient. The number of people who have dementia is currently estimated at 47.5 million.
Nvq Level 3 Dementia Research Paper
436 Words | 2 PagesThere are different types of dementia and are described as follows: Fig 1.2 (a) different types of dementia with their percentages There are different types of dementia are Alzheimer’s, vascular, mixed, dementia with lewy’s body and frontotemporal dementia etc. and there are other types of dementia too such as AIDS dementia, Parkinson’s dementia etc. The Alzheimer’s is most common form of dementia. Let us describe the each of them in detail: Alzheimer’s dementia: Fig 1.2(b) area of brain affected and cross-section that is seen from the front in Alzheimer’s dementia.
Medical Assistant Application Essay Examples
433 Words | 2 PagesVillegas Although it was not that long ago that I started doing research, Dr. Villegas has given me the privilege of working in his lab. He is currently conducting research on a rat model of Alzheimer’s disease (AD). Working with Dr. Villegas has allowed me to learn new scientific methods and facts. Such methods and facts include, but are not limited to, tissue sectioning, electrode implantation, and recording data.
Alzheimer's Day Myths And Misconceptions
652 Words | 3 PagesAlzheimer’s disease is a specific cognitive impairment that falls under the dementia umbrella. Currently there is no cure and researchers are still looking to find the cause for diseases like Alzheimer’s. It is important, as the baby-boomer generation ages, to make sure the general public is educated on common myths and misconceptions about dementia. 1.
Understanding Alzheimer's Disease
930 Words | 4 PagesAlzheimer 's is a disease that interferes with normal function of the brain related to memory and other important functions, and also deteriorates the brain. How exactly does the brain just deteriorate on itself? The answer to that question has to do with two things called plaques and tangles. Plaques are clumps of protein also referred as beta-amyloid that destroy brain cells in a couple different ways. One for examples is cell-to-cell communication, the process by sending and receiving signals between cells that initiate a certain reaction.
Medical Model Of Dementia Essay
766 Words | 4 PagesDementia is a disorder which causes the brain cells to deteriorate therefor causes a decline in several symptoms and affects a person’s mentality, capacity and how they go about their everyday life. NVQ 1.2 2) Describe the functions of the brain that are affected by dementia. There are many brain functions affected by dementia depending on which form of dementia the individual has. The temporal lobe’s functions affected are Memory loss for example forgetting things you have just been told or something you have just said so repeating yourself several times, balance, posture and vision can also be affected due to decline in health of the temporal lobe. Frontal lobe affects behaviour for example becoming withdrawn.
Informative Speech On Dementia
1021 Words | 5 Pagesa. Like speaking to someone b. Remembering a person’s name c. And the ability to pay attention to what is going on around you II. Today we are going to look at three different types of Dementia which are Alzheimer’s, Vascular Dementia, and Frontotemporal Dementia. Transition:
Alzheimer's Disease Informative Speech Outline
1191 Words | 5 PagesStudent Name: Kayla Stradomski Course # and Section/Time: COMM 101 DAH; Monday, 11:00 a.m. - 1:50 p.m. Topic: Alzheimer’s disease General Purpose: To inform Specific Purpose Statement: To educate my audience on the aspects of Alzheimer’s disease. INTRODUCTION Attention Getter: Can you imagine your life if your memories and cognition slowly started deteriorating?
Summary Of Aging With Grace
793 Words | 4 PagesIntroduction Alzheimer’s is a chronic neurodegenerative disease that usually starts slowly and gets worse over time. The most common early symptom is difficulty in remembering recent events or short memory loss. As the disease advances, symptoms can include difficulty with language, disorientation, mood swing and behavior problems. As a person 's condition progressed, they often withdraw from friends and family. Slowly, bodily functions deteriorated and eventually death occurs.
Alzheimer's Family Case Study
942 Words | 4 PagesAccording to our textbook, while evaluating the family genetic history, attention to tobacco use, heavy alcohol use, coronary heart disease, hypertension, stroke, diabetes, obesity, blood disorders, breast/ovarian cancer, colon cancer, sickle-cell anemia, arthritis, allergies, drug addiction, mental illness, suicide, seizure disorder, kidney disease and tuberculosis is essential (Jarvis, 2016, p. 53). Of the diseases listed, the ones included in his family history include; coronary artery disease and hypertension. These diseases certainly are areas of concern as JK has the risk of developing them. The adult participant JK has a very high risk of developing coronary artery disease like that of both his maternal grandfather and grandmother.
Neuropsychological Disorders Cause Brain Trauma
440 Words | 2 PagesBrown, Gotham & Marsden (1987) conducted a study to show how cognitive impairments can be observed in people with Parkinson’s disease. They found that the deficits of Parkinson’s disease have a close similarity to damage of the prefronatal cortex. When patients were off levodopa they had an impairment of verbal fluency. Huntingtons disease is a motor disorder that is passed down from generation with rapid deteriation that starts of as a slight fidgetiness and can cause dementia. Bossy-wetzel, Petrilli & Knott (2008) state that due to the fact that Parkinson’s disease occurs so late in life, the effect on the brain that it has is not entirely
Schizophrenia Neurodegenerative Model
795 Words | 4 PagesInitially, there was less support of the degenerative model because there was a lack of technology to analyze brain matter and thereby studies that could document the loss of brain matter. But, once the capacity of non-invasive neuroimaging technology increased in the late 20th century, there was a boom in such studies. The degenerative model argues that over the course of illness, normal structures in the brain deteriorate (Davis 1999, Liberman 1999, Wyatt 1991).
The Bear Came Over The Mountain Analysis
1354 Words | 6 PagesThe Bear Came Over the Mountain is a short novel by Alice Munro, first published in The New Yorker magazine in 1999 and later in 2001 in book form, called Hateship, Friendship, Courtship, Loveship, Marriage, where another short stories of Munro can also be found. There is also a movie based on this story, called Away from Her, directed by Sarah Polley. The story is about a husband (Grant) and wife (Fiona), who have been married for almost 50 years. However, Fiona starts to show the early symptoms of Alzheimer’s disease, which by time only gets worse. She gets into a nursing home, where she falls in love with a man (Aubrey), whom she knew from when she was young.
The Notebook Movie Analysis
1577 Words | 7 PagesIt is a de-generative disease of the brain that leads to a condition called dementia” (in-text citation for a journal).
Dementia Reflection Model
1391 Words | 6 PagesDementia is one of the most feared diseases and expensive to society currently. It is defined as a clinical syndrome of acquired cognitive impairment that determines decrease of intellectual enough capacity to interfere social and functional performance of the individual and their quality of life. It is a known fact that patients tend to express themselves through their behaviour and expect their carers to understand this notion. The diverse kinds of causes of different behaviours are inability to communicate, difficulty with tasks, unfamiliar surroundings, loud noises, frantic environment, and physical discomfort. Many diseases can cause dementia, some of which may be reversible.
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