9. Shukla S, Khanna KR, Singh SP (1995) Alkaloid spectrum of opium of a cross between P. somniferum and P. setigerum. International Journal Pharmacy 33: 228-231. 10. Shukla S, Singh SP, Yadav HK, Chatterjee A (2006) Alkaloid spectrum of different germplasm lines in opium poppy (Papaver somniferum L.).
Chembu Parpam - Gunapadam (Thathu Jeeva Vaguppu) 43. Pirammi Nei - The Pharmacopoea of Hospital of Indian medicine 44. Mahaaveera Mezhugu - The Pharmacopoea of Hospital of Indian medicine 45. Inji Legium - The Pharmacopoea of Hospital of Indian medicine 46. Agathiyar Kuzhambu - The Pharmacopoea of Hospital of Indian medicine 47.
SherryS. et al Thedevelopmentof urokinaseas athrombolyticagent.Mamtenanceof asuvtamedthrombolyticstatein man by It>intravenousmfusion. 1 Lab Clm Med 1965;65.713. 18 SchmutzlerR. HecknerF, Kortge P. ZurthrombolynvchenThcrapie des fnschenHerzintarktesI.
Background: Adjuncts to local anaesthetics for brachial plexus block may enhance the quality and duration of analgesia. Midazolam, a water-soluble benzodiazepine, is known to produce antinociception and enhance the effect of local anaesthetics when given epidurally or intrathecally. Aim: Study was to assess the effect of Midazolam added to brachial plexus block by supraclavicular approach. Materials and Methods: A prospective, randomized, single blinded study was conducted on 100 ASA Grade I or II adult patients undergoing upper limb surgeries under supraclavicular brachial plexus block. Patients were randomly divided into two groups.
In the 1960s, Grünenthal GmbH developed tramadol. It has an analgesic potency that is about one tenth of that of morphine. In addition to its pain relieving properties, it has anti-depressive and anxiolytic properties (Kusari ,S., etall,2015). Tramadol 's metabolism occurs in the liver by demethylation, which is mediated by CYP3A4 and CYP2B6, glucuronidation, and sulfation. Metabolism of tramadol via CYP2D6 result in the generation of an active metabolite
ROLE OF SUPPORTIVE THERAPIES IN ANO-RECTAL DISEASES Suppositories Suppositories are inserted into the lower rectum by way of the anus, where they are melted and absorbed. It acts like an ointment but in addition, has the effect of the oral medication. It is said that ointment has an on the spot outcomes, whereas suppositories have a lasting result. Nevertheless, suppositories can lead to anal canal trauma and a persistent feel of defecation. Haemorrhoids suppositories are a traditional mode of getting drugs into the physique, and haemorrhoid suppositories are being used dating back from Hippocrates, one of the founding fathers of Western medicine, who described a process of utilising reusable suppositories.
After oral administration, it metabolized in the liver, lead to formation of the 5-hydroxymethyl derivative, active metabolite. The 5-hydroxymethyl metabolite, which exhibits an antimuscarinic activity similar to that of tolterodine, contributes significantly to the therapeutic effect. The main effects of tolterodine are an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, consistent with an antimuscarinic action on the lower urinary tract. Solifenacin is a competitive muscarinic receptor antagonist by preventing the binding of acetylcholine to these receptors, solifenacin reduces smooth muscle tone in the bladder, allowing the bladder to retain larger volumes of urine and reducing the number of incontinence. Fesoterodine is a prodrug.
(1951) after proceeding for calibration of caesin). Ascorbic Acid: Ascorbate was determined by the colorimetric method of Mindlin and Butler (1938) by following the decolorization of 2,6 dichlorophenolindophenol in metaphosphoric acid after proceeding for calibration of Ascorbic Acid. Peroxidase Activity: Total peroxidase activity was measured using guaiacol as donor by the method of Maehly and Chance (1954). Results: The effect of ACTH on hypophysectomized rats injected with 20µ of ACTH is shown in fig. 1.It is seen that as the depletion of AA ensures within 10 minutes after ACTH injection the peroxidase activity tends to show an increase.
While, the anti-inflammatory activity was assessed by two different models; the carrageenan-induced paw edema and the carrageenan-induced peritonitis in which the levels of total leukocyte count (TLC), neutrophil count, prostaglandin E2 (PGE2) and interferon gamma (INF-γ) were measured in the peritoneal exudates. The results revealed significant protection in all the treated groups; however, the combination of EVOO with IBU at its therapeutic dose showed superiority over the two compounds when used separately. Conclusion: Using extra virgin olive oil with the therapeutic dose of ibuprofen showed synergistic effect in controlling the cardinal signs of acute inflammation rather than using the NSAIDs