Proliposomes: It involves forming a thin lipid film on a bed of water soluble carriers like sorbitol, mannitol.This increases the surface area for formation and drying of lipid films. Once dried these are called as proliposomes having better stability. On dissolving in aqueous medium the carrie dissolves resulting in the formation of liposome vescicles. COMPOSITION: 1. Glycero phospholipids are majoritily used.
1.6.2. Instant release Dissolution rate of the drugs commonly selects its rate and amount of bioavailability. Due to the improved solubility and wet capability of the drugs concluded the development of inclusion complexes, Hydrophilic cyclodextrins aids in cumulative the oral bioavailability of steroids, non- steroidal anti- inflammatory drugs, antiepileptic, anti -diabetics, vasodilators. 1.6.3. Sustained release Alkylated and acylated products of Cyclodextrins which are hydrophobic in nature are used as gentle release movers for water soluble drugs.
Abstract New copolymeric membranes was offered for the efficient delivery of antibiotic drug using the synthesized chitosan–copoly(semicarbazide–formaldehyde–phenylhydrazine) blend membranes. The membranes were prepared by solution casting technique and characterized by elemental, spectral and scanning electron microscopy to establish the chemical structure and morphology. Scanning electron microscopy clearly reveals that the increased porosity in the polymeric network enables rapid swelling; leads to faster diffusion which facilitates effective drug release. The composition of chitosan content also governs the swelling behavior i.e. increased chitosan content showed excellent swelling behavior leads to profound drug delivery.
b-Amylase is an exo-acting enzyme It hydrolyses alternate glycosidic linkages, yielding maltose. Some of the microorganisms reported to produce b-amylases include Bacillus polymyxa, B. cereus, B. megatarium, Streptomyces sp., Pseudomonas sp. and Rhizopus japonicas The fungal amylases are preferred over other microbial sources because of their more acceptable acceptable GRAS (generally regarded as safe) status. PH: Earlier reports suggest that amylases are produced by fungal organisms maximally in acidic medium,Enzyme production started at pH 3.0 and cease at pH 8.0. STARCH CONCENTRATIONS:There was progressive increase in the productivity of α-amylase and glucoamylase by the isolates as the starch concentration increased.
For many applications, silica are not the correct and suitable alternatives. However, the study reported that silica have problem in interacting and dispersing with the rubber matrix which are consist of hydrocarbons due to their polar surface. This causes silica to be known with its low reinforcement level with NR. (Rattanasom et al., 2006). Despite all the advantages of starch, they also have few weakness which prevent them to act as reinforcing filler of NR efficiently.
Therefore, I personally believe “Prevention is better than cure”. Like many diseases can be prevented by following simple hygiene procedures like washing hands and also by maintaining clean surroundings. Since time immemorial man has achieved wonderful things in various fields like technology, space research but medicine proves to be most challenging of all, with new strains of organisms emerging at a threatening rate. So, creating awareness among people about various preventive measures and by contributing to research in the healthcare would make the world
Stabilizers such as surfactants or phospholipids are necessary for controlling the desired particle size. This method is not very convenient for large scale production but still can be used for production of soft drugs. SkyePharma Canada Inc. uses this process for production of submicron particles of poorly soluble drugs
These polymers however have high molecular mass due to which it becomes non bio degradable. This contributes to the fact that an alternative plastic which has a biodegradable composition has to be made so that it would be able to reduce the amount of plastic that would remain on earth, polluting its soil and water bodies. Polymers are molecular structures that contain a series of repeating units bonded together. All types of plastics are made up of polymers. Biobased plastics are plastics made from organic sources such as vegetables and animal oils.
If the amino acid is hydrophobic it would have a greater affinity to the solvent, even though the solvent contains water. This is because the stationary phase is made up of cellulose which absorbs the water thus causing the hydrophobic amino acids to have a greater affinity to the mobile phase. Hydrophilic amino acids would have a greater affinity to the stationary phase causing it to “stick” to the starting point. The amino acids are carried upward by the mobile phase in what is called capillary action. Since amino acids are colorless ninhydrin is sprayed to give the amino acids a purplish color making it more visible to measure the distance traveled.
Similarly, inaccessibility to avant-garde technology will hamper productivity and the quality of the products and services. The factors mentioned above have a major impact on an organization. Management thinkers over the years have brainstormed to get some answers on how to anticipate changes and prepare an organization to survive a sudden change in milieu, which to an extent have been successful, but still organizations around the world should avoid complacency and retrospect to find chinks in their armor, which if ignored can prove