Introduction and Background
Bixa Orellana (achuete) from the family Bixaceae is a shrub or bushy tree grown from either seeds or cut lings which ranges from 3 to 10 meters in height that can be found in regions spanning the globe. It requires full sunlight and protection from the wind. The plant grows equally well in lowlands and mountainous regions or areas of higher elevation and is cultivated in warm regions of the world, such as India, Sri Lanka, Java, Philippines, southeastern Africa and Dominica, and is commonly planted in Florida as an ornamental. Variety of common names were given for B. Orellana (achuete) in different places depending where it flourished. It is most frequently called "annato" in the North America and "achuete" in the Philippines.
B. orellana (achuete) is commonly used in culinary to provide a red-tinged colorant use. Its seed is used all over the world dye for coloring rice, cheeses, soft drinks, oil, butter, and soup. Also, it has long been used by indigenous communities in Brazil and other tropical countries for several biological applications (D.Vilar, M. Vilar, T. Moura, 2014), which indicates its potential use as an active ingredient in pharmaceutical products such as a traditional remedy for a variety of conditions, including diabetes, jaundice, snakebite, indigestion, heartburn, hypertension or high blood pressure, and antibacterial. All parts of the plant have been used, including the roots, leaves, seeds, and dried pulp of the