The syndrome is characterized by the association of lymphedema, intestinal lymphangiectasia, intellectual defecit and facial dysmorphism. Here is a case presented with distension of abdomen with ascites, bilateral pedal oedema, macrocephaly, left half facial edema, left half hypertrophied tongue, dental anamolies. acanthosis nigricans, acrochordons and syndactyly consistent with a diagnosis of Hennekam syndrome. The diagnosis of Hennekam is
Simillar dermal collections of adipocytes on histopathological examination are also present in some melanocytic nevi,pedunculated lipofibromas and in Goltz syndrome. Lipofibromas contain fat cells, but no skin appendages in the dermis. In the case of Goltz syndrome, there is absence of collagen in the atrophic dermis and skin appendages are absent. The precise etiopathogenesis of NLCS is not
Dwarfism is usually divided into two categories; disproportionate dwarfism which is where some parts of the body are small and some parts are average or above average and this type prevents the bones from developing. The other type is proportionate dwarfism where all the body parts are small and are the same size. This type is usually apparent at birth or early childhood when growth and development do not happen normally. Dwarfism remains a rare disease and it only affects about 200,000 people in the population. There were approximately 5000 achondroplasts in the United States of America in 1971 and approximately 65000 in the
MORPHOLOGY Rosenblatt et al in 1942 examined them by electron microscope and demonstrated that the tubercle bacilli vary in length from 0.8 to 5.5pm and width from 0.2 to 0.6pm. However there are numerous variations from different ultureand even in same culture. Predominant form is rod shaped with rounded or slightly flattened ends, but curved bean - shaped or oval forms are common. Human form is longer and slender, and the bovine form is short and stumpy. Avian type is pleomorphic on morphological grounds alone organisms cannot be identified.
 (Safety) Pantoprazole use is safe, also if it is used for long term.  Most common side effects are Headache, nausea and diarrhea which will fade away during the course of treatment.  A very rare side effect of PPI is increased risk of Osteoporosis.  However, recent U.S. Food and drug administration (FDA) studies revels that this risk is evident only in use of PPIs over a year and above and only found in elderly people.  Thus, EH is unlikely to exhibit such rare side effect at recommended course of treatment.
184.108.40.206. Symptomatic treatment of ADPKD Cases of ADPKD require a symptomatic treatment by prophylactic and supportive measures such as tight blood pressure management; also include adequate pain control, antibiotics for urinary tract infections, sufficient fluid intake, and avoidance caffeine and smoking. Urinary tract infections could be treated by using cyst-penetrating antibiotics, which is lipophilic agents penetrate the cysts consistently such as trimethoprim-sulfamethoxazole and fluoroquinolone (Elzinga et al., 1987 and Elzinga et al., 1988). 11.126,127, Whereas cyst hemorrhages require a careful administration with bed rest, analgesics and water. Also cases of nephrolithiasis require prophylactic measures, which include good water intake, such as potassium citrate was suggested for three causes of stones associated with ADPKD, uric acid lithiasis, hypocitraturic calcium oxalate nephrolithiasis, and distal acidification defects (Torres et al., 2007).
Platelet adhesion is mediated by von Willebrand factor(vWF), which sticks circulating platelets to the area of damaged vessel wall by binding to its receptors located in platelet membrane glycoprotein Ib. The adherent platelets then undergo a “release reaction,” adenosine diphosphate(ADP), thromboxane A2(TXA2), and other components which act in concert to recruit and activate additional platelets from the circulation to the site of vascular injury. In the process of platelet aggregation (platelet-platelet interactions), fibrinogen (or vWF under conditions of high shear stress) mediates the final formation of an occlusive platelet plug, If the plug contains only platelets it is termed a white thrombus; if red blood cells (RBCs) are present it is called a red thrombus. (2) Negative feedback of the plug formation is controlled by prostacyclin released by the endothelium and this reduces platelet aggregation. White blood cells(WBCs) in the area also release proteins that prevent the clot getting out of control.
It may appear on the skin in a number of different ways, although it usually develops on the chest. One of the clinical presentations is called carcinoma erysipeloides, which appears as pink or red raised areas of skin resembling a severe skin infection known as erysipelas or cellulitis. Another form, carcinoma telangiectoides, appears as red-violet papules. Carcinoma en cuirasse presents on the chest as a firm area of skin resembling the texture of an orange
The effectiveness of fluoride water is greatest for deciduous dentition, less caries in fluoridated communities with a range of 30-60 percent. In the ages between 8-12, is about 20-40 percent less caries in the mixed dentition and 15-35 percent less caries in adolescents between the ages 14-17 (E Newburn, 1989, p. 279). Water fluoridation was associated with reduction in dental caries experience about 29% substantially, and across all age groups 32% in permanent caries experience. The early studies reported that decay experience reduction in almost about 50% or more. In the early 1970s the fluoridated toothpaste has very important source of fluoride.