Bronchogenic Carcinoma Research Paper

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INTRODUCTION:
Bronchogenic carcinoma is the most common malignancy in the world, accounting for 7% of all deaths in men and women. It is the leading cause of death in industrialized countries and also rising at alarming rates in developing countries.[1]In Pakistan cancer of the lung has been ranked the most frequent malignancy in men in Karachi in the entire 1995- 2002 period. In the 1998-2002 period the incidence rate increased to 25.5 per 100,000 (males) and 4.2 per 100,000 (females). [2]Extensive epidemiologic data clearly establish cigarette smoking as the major cause of lung cancer. [3]
Most cases of lung cancer present at an advanced stage and therefore it is important to develop means of screening for early diagnosis. Computed tomography
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OBJECTIVE
To evaluate the accuracy, sensitivity and specificity of CT scan in diagnosing bronchogenic carcinoma taking histopathology as the gold standard.

OPERATIONAL DEFINITION
Bronchogenic Carcinoma All those patients who had a pulmonary lesion on X ray along with history of symptoms like hemoptysis, weight loss, and recurrent pleural effusion etc. will be taken as possible cases of bronchogenic carcinoma.

Diagnostic Accuracy of the investigation will be assessed via sensitivity, specificity, positive predictive value and negative predictive value of CT scan taking histopathology findings as true negative or positive.

MATERIALS AND

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