ipl-logo

Rheotaxis In Bull Sperm

1639 Words7 Pages

4. Discussion: The present study has collectively evaluated the presence of CatSper channels and their characteristics in bull sperm, thus providing a novel insight into the cellular mechanisms that induce hyperactivation and rheotaxis in bull sperm. The main finding of this study was that the known calcium channel inhibitor Mibefradil produced an inhibitory effect on bovine sperm hyperactivation. This effect occurred as a delayed induction of hyperactivation. Furthermore, it was found that Mibefradil produced an inhibitory effect on sperm progression through a microfluidic device in comparison to the caffeine controls. This finding in conjunction with the observed stimulatory effects of high extracellular pH, NH4Cl and caffeine indicates that …show more content…

al, 2014) have investigated the effect of rheotaxis on bull sperm navigation through a microfludic device. Tung et. al, (2014) reported rheotactic behaviour of bull sperm in grooved microchannels mimicking the cervix walls in the female reproductive system. It was found that these grooves helped sperm cells to migrate against fluid flow. Furthermore, the speed of sperm cells swimming against the flow was found to decrease with an increase in the flow rate inside the microchannel. In this current study, rheotaxis was also found to play a role in sperm progression though the microchannel. Using the optimum flow rate for the device it was found that untreated sperm progressed though the device and exhibited positive rheotaxis. This indicates that rheotaxis could play an essential role in the long distance navigation of bull sperm through the female reproductive tract to the oocyte (Miki et. al, 2013). This finding is substantiated by a similar finding in studies by Kantsler et. al …show more content…

al, 2014). El Sherry et. al (2014) concludes that flow velocity plays an important role in regulating sperm rheotactic behaviour. El Sherry et. al (2014) suggests that mechanical effects may exist through mechanosensing ion channels (MSCs) due to fluid shear stress increasing on the membrane of sperm head with an increase in the liquid velocity. MSCs are stretch activated channels that respond to mechanical stress on the cell membrane by allowing certain ions to enter the cell (Sachs, 2010). When a sperm swims against the flow, it experiences an increase in liquid pressure at its most upstream tip where the liquid is brought to a halt. This pressure rise increases with the flow velocity. In addition, the fluid drag / shear stress on sperm head also increases with flow velocity (El-Sherry et. al, 2014; Kantsler et. al,

Show More
Related

  • Cald1 Unit 1 Research Paper

    209 Words  | 1 Pages

    It binds and stabilizes actin filaments, as well as regulating actin-myosin interaction in a calcium (Ca2+)/calmodulin (CaM)- and/or phosphorylation-dependent manner.(17) The domain of this protein includes binding activities to Ca++-calmodulin, actin, tropomyosin, myosin, and phospholipids. As

    Read More

  • Summary Of Chapter 8 And 9 Of Your Inner Fish

    746 Words  | 3 Pages

    The arrangement of holes, spaces, and membranes from fish to man

    Read More

  • What Are The Ethical Issues In The Immortal Life Of Henrietta Lacks

    890 Words  | 4 Pages

    Endocrine Reviews. The Endocrine Society. Web. 18 Aug.

    Read More

  • Big Dick Pills Research Paper

    1035 Words  | 5 Pages

    With this pills, they work in such a way that that they foster your sex drive, increase your dick size and get a harder erection. Furthermore,there are some natural ways that one can get his dig bigger .Most of them comprise some normal exercises in your body and your dick. Some of the big dick pills include VigRX Plus. This type of pill has been scientifically proven

    Read More

  • Primate Motor Cortex Summary

    309 Words  | 2 Pages

    Also a cell’s activity was not modulated by a particular directional movement, they wanted to quantify the relations between cellular activity and the direction of movement. To get at these questions, Georgopolos et al. (1982) recorded extracellular

    Read More

  • Vimax Research Paper

    530 Words  | 3 Pages

    Reviews of Vimax acquaint that Vimax is one of the able accustomed herbal pills, which is acclimated for macho accessory that helps in accretion the penis breadth and girth. They are aswell accepted to accept absolute furnishings on animal desire, animal health, and helps in accomplishing stronger erections. The pills accept been formulated by demography herbs from all about the apple and accept accepted to plan and accord adapted results. Vimax uses the aforementioned blazon of herbs that is frequently begin in Polynesia, which is accepted for its Mangaian association area men accept sex an boilerplate of 3 times a night. This is what you may not wish but it is still acceptable to apperceive that you can accretion aback your animal adeptness substantially.

    Read More

  • Cow's Hair Whorl Experiment

    1568 Words  | 7 Pages

    The rates of this cattle was determined by their reaction to the operation by thrusting or struggling to get fee. The rating was written down next to the cow’s number, weight, gender, and the height of the whorl on the cow’s head. In the charts that were created for this experiment, the cattle were separated

    Read More

  • Brumby Control In Australia

    1514 Words  | 7 Pages

    The Australian brumby is an iconic species, often associated with an earlier time in Australian history with a sense of romanticism. However it seems that this once revered species is now seen as a domestic threat to agricultural communities in New South Wales and Victoria. Wild brumbies came about in the countries’ early years when introduced horses escaped from poorly fenced paddocks or were lost during cattle musters. Over time these herds have growth rate of 20% per year in non-drought years (Lundie-Jenkins. G, Maag.

    Read More

  • Why Crime Fell In The 1990s: The Decrease In Crime

    783 Words  | 4 Pages

    (Levitt, 2004, p. 182). His statistics are compelling, but the reasoning seems slightly irrelevant, as argued by Baumer and

    Read More

  • Negative Effects Of Birth Control Pills

    958 Words  | 4 Pages

    Second, the liver pumps out a protein called the sex hormone-binding globulin (SHBG), which gloms onto sex hormones (including testosterone) like bargain shoppers on Black Friday sales. But while OC’s lower testosterone levels in all women, they lower libido only in some, Dr. Keder says. And even if the Pill does affect your mojo, plenty of other factors — like anxiety about getting preggers — affect it, too. If you have serious problems below the belt, ask your doctor about switching to a different

    Read More

  • Bed 3110 Unit 3 Lab Report

    2403 Words  | 10 Pages

    Velocity was calculated by finding the change in position of the indicators between each frame and multiplying by the frame rate (30 fps) and maximum instantaneous velocity was paired with the weight applied to fit to the Hill equation. Guesses for F0, a, and b were taken from the isometric experiment and literature values.6 RESULTS Figure 3: Length-Tension behavior of the gastrocnemius of a Rana pipiens compared to expected data from peer-reviewed literature. The gastrocnemius of a Rana pipiens (n=1) was stimulated in situ isometrically. Experimentally measured tensions (red squares) were plotted with literature values (green circles). Tensions at corresponding normalized lengths were compared between literature and measured values and were comparing using piecewise linear regression in groups of three yielding an overall r2isometric = 0.956033 between measured values and expected results from

    Read More

  • Gummy Bear Lab Report

    1804 Words  | 8 Pages

    The Effect of Osmosis on Gummy Bears In this lab, we will examine the effect of the process of Osmosis on gummy bears placed in 5 different solutions. In living things, the cell membrane is what controls the output and input of the cell. In addition, it is selectively permeable, meaning it can differentiate molecules regardless of size. In non-living things, however, it is semi-permeable, meaning it allows certain substances to enter and exit the object without being able to identify it.

    Read More

  • Arguments Against Fluoride

    1500 Words  | 6 Pages

    Fluoride and male fertility The majority of all water supplies contain a certain amount of fluoride and approximately half a million people in the UK alone receive naturally occurring fluoridated water. Add to this this 5.5 million of the UK population that receive water with an unnatural and manufactured fluoride concentration and you’ll no doubt agree that’s a lot of people receiving a daily dose of fluoride. It isn’t just the UK that’s affected however, with Europe and the U.S both adding fluoride to their water. In the U.S alone a whopping two thirds of the drinking water is fluoridated. What’s now becoming an ever-increasing concern however, is the fact that men’s fertility is at risk with fluoridated tap water.

    Read More

  • The Effects Of Temperature On Heart Rate And Strength Of Contraction

    2152 Words  | 9 Pages

    Background: Explain on the cellular level how dropping warm Ringers solution on the frog’s heart would affect the cells of the SA node. Dropping warm Ringers solution on the frog’s heart would increase the heart rate because the calcium channels open faster. Explain on the cellular level how dropping warm Ringers solution on the frog’s heart would affect the cells of the contractile muscle of the ventricles. Dropping warm Ringers solution on the frog’s heart would increase the heart rate because the actin binds to the myosin more quickly due to the calcium channels opening faster leading to faster contraction of the heart.

    Read More

  • Organ Bath Experiment

    1445 Words  | 6 Pages

    Later, 5ml of 1 x 10-6 M of mepyramine was added into the reservoir containing 1000ml of Krebs-Henssleit solution to produce a FBC of 5.0 x 10-9M. It was equilibrated with tissue for 10 minutes by flushing into the organ bath. After that, the steps above were repeated to test tissue response using 5ml of 1 x 10-5M and 1 x 10-4M of mepyramine. The experiment was repeated by replacing mepyramine with SIPBSDrug A as the antagonist. Lastly, concentration-response curve with Hill-Langmuir equation and Schild Plot were plotted using Bio-Graph. KB and pA2 values for mepyramine and SIPBSDrug A were calculated based on Schild plots and Gaddum

    Read More

More about Rheotaxis In Bull Sperm

Open Document