Caffey's Disease Case Study
ABSTRACT: Caffey’s disease or Infantile Cortical Hyperostosis is a rare, mostly self-limiting disease, affecting young infants less than 6 months of age. It is characterized by a triad of soft tissue swelling, cortical thickening of the underlying bone and hyperirritability. The mean age of presentation is 9-11 weeks of age. It typically involves the mandible, clavicles, ribs and diaphysis of the long bones. We report a case of Caffey's disease presenting at an early age of 6 weeks, affecting long bones, with symmetrical involvement of ulnar bones, and thrombocytosis an uncommon presentation. On follow up for 48 months there were no recurrences. Caffey's disease, also called as infantile cortical hyperostosis (ICH), is characterized by an episode of massive sub periosteal new bone …show more content…
Caffey J. Infantile cortical hyperostosis; a review of the clinical and radiographic features. Proc R Soc Med 1957;50:347-54. 8. Kaufmann HJ, Mahboubi S, Mandell GA. Case report 39. Skeletal Radiol 1977;2:109-111. 9.Gentry RR, Rust RS, Lohr JA, Alford BA. Infantile cortical hyperostosis of the ribs (Caffey's disease) without mandibular involvement. Pediatr Radiol 1983;13:236-8. 10. Ranadheer M, Murari SB, Sujith N, Jayanthi, Sudhakar P, Rao VP. Scintigraphic and radiological correlative and confirmative features obviating invasive biopsy in Caffey's disease Indian J Nucl Med. 2010;25:20–22. 11 . Agrawal A, Purandare N, Shah S, Rangarajan V. A rare variant of Caffey's disease - X-rays, bone scan and FDG PET findings. Indian J Nucl Med 2011;26:112-4. 12. 14. Katz JM, Kirkpatrick JA, Papanicolaou N, Desai P. Case report 139 Infantile cortical hyperostosis (Caffey disease). Skeletal Radiol 1981;6:77-80. [PUBMED] * 13. 15. Pohl A, Orha L, Dragoi AM. Infantile cortical hyperostosis (Caffey disease). Rev Pediatr Obstet Ginecol Pediatr 1989; 38: 369-373. 14. 16. Dutta S, Jain N, Bhattacharya A, Mukhopadhyay K. Infantile Cortical Hyperostosis. Indian Paediatr
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