Organic Activity Of Ginger Essay
ANTIMYCOTIC ACTIVITY OF ZINGIBER OFFICINALE EXTRACTS ON CLINICAL ISOLATES OF CANDIDA ALBICANS
Type of manuscript: Research article
Running Title: Zingiber Officinale Extract and its Antimycotic activity on clinical isolates of Candida albicans.
Trinaina Somas Kandhan
Undergraduate Student
Saveetha Dental College, Saveetha University, Chennai, India.
Dr. R.V.Geetha
Asso. Professor
Department of Microbiology, Saveetha Dental College, Saveetha University,Chennai, India.
Corresponding Author
Dr.Geetha
Asso. Professor
Department of Microbiology, Saveetha Dental College
Saveetha University
162, Poonamallee High Road
Chennai 600077
Tamil Nadu, India
E-Mail :rvgeetha2015@gmail.com
Telephone Number : +919710456203.
INTRODUCTION:
In the past few
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Among these volatile essential components, which constitute gingerol and shagelol have been accounted for antimicrobial activity of ginger.19According to the study performed by Atai.Z et.al, which was carried out to find an alternative for Nystatin, the study was designed based on laboratory investigations to investigate the anti fungal activity of Zingiber officinale (Ginger) on Candida albicans. Candida albicans was obtained from Iranian microbial collection and was confirmed by Germ Tube formation test. Ethanolic ginger extract was prepared. The anti-fungal activity of the extract was determined using Agar dilution and disc diffusion techniques. Data were analysed by ANOVA test. The results showed that the ethanolic extract was effective on Candida albicans (2 mg mL-1) at the concentration of 1:5. The study indicates that ginger extract might have promise in treatment of oral candidiasis. 10 Therefore, as the study proves, Zingiber Officinale extract is a highly potent anti fungal or Antimycotic …show more content…
The positive control (fluconazole,amphotericin B) produced significantly sized inhibition zones with Candida albicans. The inhibitory zone was measured with respect to different concentrations of the extracts which included 2000µg/disc, 1000 µg /disc and 500 µg /disc at both room temperature and cold temperature (4-8°c). The inhibition zones were evaluated at 24 and 48 hrs. The results of this study revealed that the ginger oil has pronounced inhibitory activities against Candida albicans. This result is comparable with other studies which have shown that Zingiber Officinale has a broad antibacterial activity.Since Zingiber Officinale is easily available and well- tolerated, it can be incorporated into medications for topical anti fungal therapy as
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