Sample Case Study Of Pharmacokinetics
Pharmacokinetics: Oral administration; When the drug gets administered observation of the movement of the drug portrayed that 15 to 41mg/ml reached maximum concentration in 0.85 to 1.25hours with the additional fact that taking in a high fat meal decreased the absorption rate. The half-life of the drug is 0.76 to 1.35 h, with the metabolism of the drug pilocarpine occurs in the neuronal synapses and probably in the plasma and then gets eliminated in the urine with minimal degradation occurring. The drug pilocarpine has an onset of action occurring in 20 minutes and lasts up to 3 to 5 hours reaching its peak in one hour. If the patient has any problems associated with the renal function the rate of pharmacokinetics wouldn’t get effected on this drug, However, if the hepatic function is impaired the clearance of ths drug would decrease which results in an increase in the maximum concentration and the amount of time to reach the half-life. …show more content…
The action of the pilocaripne would be of about 0.5% to 4% depending on the strength of the pilocarpine used. The time it took to reach the maximum concentration, which was 3.7mg/ml, was of about 0.5 to 1 hour. Sustained release of pilocarine was observed due to the ocular system, of about 20 to 40 mcg/hour, only reaching the maximum effect of 1.5 to 2 hours after the application of the
Low Back Pain Case Studies
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