Despite these short term effects, the main reason why people take meth is for the euphoria that comes from the flood of dopamine in the brain. However, although meth makes the user feel good temporarily, the euphoric "high" from the drug starts and fades quickly, leading the user to use meth several times in a row. Once addiction sets in, the true consequences of using meth begin to show itself.
However, two drugs that are very similar but yet very different are crack cocaine and powder cocaine. These two drugs are essentially based on the same chemical composition, but one is far more dangerous than the other. In order to comprehend why crack cocaine is more dangerous than powder cocaine we must first understand the history of these drugs, and the detrimental effects they have on the human body. First we will discuss the drug benzoylmethylecgonine, better known by its street name of coke. “Cocaine is a purified extracted from the
Introduction: Mexico is known for its big connection between drugs, money, and violence. Money from drugs is a major part of the economy in Mexico. Most illegal drugs enter the U.S. through the southwest border from Mexico. They enter the U.S. through unsecured parts of the border, smuggling tunnels, or trafficking methods. Thousands of people are murdered throughout the year because of this dangerous business.
Beginning as a prescription drug for severe or chronic pain, oxycodone gradually becomes a silent addiction. The patients may experience less pain and a high, ultimately creating a desire for more medication. After the initial first week, the desire has moved from a simple want to a need. The body begins to crave more, as the patient desires to feel the high again. After the first few weeks of being addicted, the original dosage no longer helps.
The number of ER visits due to oxycodone pills, including Percocet, increased by over one fifty percent between 2004 and 2008. It is also estimated that about ten percent of the patients who are currently prescribed with Percocet for pain relief will continue to stick on to the drug leading to its addiction and abuse. Another unsettling fact about the Percocet abuse is that the adolescents use Percocet for recreational purposes and end up getting addicted to the drug over time. Even if they try to quit they will experience obsessive and compulsive thoughts about the drug. Considering the amount of awareness that the kids are exposed to, such miserable behavior is unacceptable and heart wrenching.
Have you ever wondered the similarities and differences between Joaquin Guzman (El Chapo) and Pablo Escobar? Joaquin Guzman and Pablo Escobar are the most popular drug lords in the entire world. Joaquin Guzman is a Mexican drug lord that leads a group known as the Sinaloa Cartel. Pablo Escobar was a Colombian drug lord that lead the Medellin Cartel. These two drug lords have earned billions of dollars from selling drugs all across the world.
Bolivia now sits alongside the biggest consumers of illegal drug in the world. Bolivia also borders the world 's producers of cocaine. According to Bogotá 's Security Secretary Daniel criminal operations in the Bronx were worth between $1 million and $2 million per month. For these gangs to be able to operate freely despite a continuous state presence in Buenos Aires ' villas, there is strong collaboration between criminals security forces and politicians, Manjon told Insight Crime. A vast majority of
Moreover, the degree of hemorrhage may appear striking and disproportionate to the external and internal evidence of injury. Here in our case also the assault might have looked minor for witnesses since the person was assaulted by hands and feet only but certainly it resulted in sub arachnoid hemorrhage of traumatic origin. Aspiration is the inhalation of regurgitated gastric contents, it commonly occurs in patients who have marked disturbances of consciousness such as that resulting from a drug overdose, alcohol intoxication, seizures, a massive cerebro vascular accident, traumatic brain injury or the use of anaesthetist.11 In this case the patient vomited due to head injury and there was also a blunt trauma to abdomen which gave rise to increase in abdominal pressure which caused regurgitation of gastric contents which in turn caused aspiration. Further the alcohol intoxication in this patient resulted in diminished reflexes. Combined effect of aspiration and diminished reflexes resulted in asphyxia caused due to chocking of aspirated vomited contents leads to death of the patient.
However, there are very distinct differences between cocaine and meth, in terms of how these drugs affect the individual both physically and psychologically. Both drugs are stimulants so they stimulate the individual and create an euphoric high, as a result of the way both drugs elevate the dopamine levels in the brain. Stimulants such as cocaine and meth cause the user to be more active, talkative, alert, less tired, exhilarated, etc. This essay will talk about each drug signs and symptoms treatment nursing management for drug abuse. Cocaine is an extremely addictive and poisonous drug and is a central nervous system stimulant (Miller-Keane).
6 Drugs that lead to these diseases are heroin, cocaine and methamphetamine. People who abuse any of these drugs have a higher probability to the exposure of HIV, viral hepatitis and other infectious agents through contact with infected blood or body fluids 7 that results from sharing contaminated syringes or engaging in unprotected sexual contact with an infected person. Apart from that, drug abuse makes the liver works harder in order to break down the poison that ingested or absorbed into the bloodstreams and filter toxins so that the body can absorb the healthy nutrients that remain. This possibly can cause significant damage to the liver as well as liver
One example is blocking neuronal transporter (NET), thus blocking the uptake of amines by nerve terminals, by competition for the binding site of the amine transporter. This raises the level of neurotransmitter in the synaptic cleft, increasing CNS activity. Morphine: In the nociceptive neurons pathway, opioid drug or also called opiates. Opioids are agonists that act on opioid receptors coupled to Gi/Go-protein-coupled receptors and exert powerful effects on ion channels on neuronal membranes. Opioids helps opening of potassium channel to cause hyperpolarization of the cell and inhibit the opening of voltage-gated calcium channels.
The hypothalamus communicates to each lobe differently. The hypothalamo-hypophyseal tract system is the specific way the hypothalamus communicates with the posterior lobe of the pituitary gland. It is a nervous system connection with direct connecting neurons. The neurons are located in the hypothalamus and then axons extend down to the posterior lobe of the pituitary gland. The neurons produce hormones that slide down the axons and end up in the posterior lobe.
Effects of heroin overdose will include the following: slow and shallow breathing, hypotension, muscle spasms, seizures, coma, and possible death. Tolerance develops when the abuser use more heroin to reach the same strength or outcome. Withdrawal, which involves regular users includes: drug craving, restlessness, muscle and bone pain, insomnia, diarrhea and vomiting, cold flashes with goose bumps kicking movements and other symptoms. Sudden changes in behavior, Loss of interest, Small, restrained pupils, rapidly nodding off, hyper-alertness periodically, shortness of breath are some signs and symptoms of heroin. There are also some signs and symptoms that are: physical, psychological, and behavioral.
For example, the MOR agonist morphine can bind which means that a ligand can be introduced and not well regulated by the body, leading to overdose (11). Research has found that enkephalins are scattered in GABAergic interneurons, with MORs and DORs inhibit granule cells because they are in very distinct subpopulations of GABAergic interneurons (11). On the other hand, dynorphins are in granule cells and dendrites and KOR agonists, which will consist of endogenous dynorphins, decrease long-term potentiation. KORs have also been found to regulate GABA release at the presynaptic sites of the neurons (K- opioid). GABA, being the main inhibitory
The short acting medications normally work in 15 minutes and can last 6-8 hours. Short acting anticholinergics are not considered relief medications because they normally take longer to work than our beta-agonist medications. Though the lists of short acting anticholinergics are short these medications are great for people with COPD. They have fewer side effects than beta-agonist drugs and they are good bronchodilators. The long acting anticholinergic drug takes about 20 minutes to work and can last up to 24 hours, although it is thought of as a “reliever” it’s long lasting effects would make it an excellent maintenance drug for patients with COPD