Chlorpromazine Research Paper

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The discovery of chlorpromazine in 1953 was the main historical milestone in the field of psychiatry. This is not only because chlorpromazine was the first drug that cured symptoms of psychosis; but it also provided clues to identify the biological basis of psychotic disorders like schizophrenia, because of its action on dopamine receptors. After the discovery of chlorpromazine, a lot of antipsychotic drugs were identified to treat psychotic symptoms. Followed by chlorpromazine, other phenothiazines including perphenazine and fluphenazine were introduced. In 1960, the first long acting antipsychotic medication, fluphenazine was introduced. Although these medications are similar in their effectiveness, they differ moderately in their adverse

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