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Clostridium Botulinum

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The bacteria by the name of Clostridium botulinum produces a special, extremely dangerous protein neurotoxin that can be a matter of life or death to the exposed individual. The basic mechanism of the toxin (which has eight serotypes) is blocking the release of a neurotransmitter Acetylcholine (ACh) at the synapse between the motor neuron and a muscle (1). By obstructing the release of ACh at the neuromuscular junction, the muscle is unable to contract thus, causing muscle paralysis. This potent toxin has therapeutic as well as cosmetologic uses. I will focus on how C. botulinum toxin is used in surgical cosmetology as well as describe how it can cause Botulism disease in humans.
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