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Conjunctiva Research Paper

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INTRODUCTION Inflammation of the conjunctiva is called conjunctivitis.It may be infective or allergic either in acute or chronic form.Types of conjunctivitis are Infective, Allergic, Chemical &Traumatic.Infective or allergic conjunctivitis present in acute form or in chronic form and are characterized by hyperemia, watery secretions (lacrimation), itching anddischarge.Hyperemia varies in degree and in distribution.The secretions vary in nature and in amount. The nature of secretion is sometimes of diagnostic importance.Infective conjunctivitis is due to bacterial, viral and fungal infections. Chemical conjunctivitis occurs due to exposure to chemicals like mercury, silver nitrate etc. Traumatic conjunctivitis is due to superficial trauma to the eye. Allergic conjunctivitis is one of the commonest …show more content…

Oral: Tablet form: 5mg once a day KETOROLAC Ketorolac tromethamine ophthalmic solution 0.5% is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs) for ophthalmic use. HISTORY Ketorolac was developed in 1989 by syntex Corp.The ophthalmic preparation was approved by FDA on 9 November 1992 and was introduced as Acular eye drops. CHEMISTRY- it is a dihydropyrrolizine carboxylic acid derivative MECHANISM OF ACTION It works by blocking the production of prostaglandin,by competitively blocking cyclo oxygenase enzyme. PHRMACOKINETICS ABSORPTION Bioavailability: 80-100% Onset: IM, 10 min; PO, 30-60 min Duration: 4-6 hr (analgesia) Peak serum time: 1-3 min (IV); 30-60 min (IM); ~1 hr (PO) Peak plasma concentration: Varies with dose and route Distribution Protein bound: >99% Vd: ~13 L METABOLISM it is largely metabolised in liver EXCRETION half life-2 to 6

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