Coronary Heart Disease Case Study

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Introduction
Coronary heart diseases (CHDs) are a common disease in the world. Coronary heart diseases are the most common disease in the United Kingdom. According to World Health Organization (WHO), 150,000 people were death from coronary heart disease in the United Kingdom per year (Martin et. al., 2011). The mortality rate of coronary heart disease is increased in Hong Kong. Heart disease is the third high mortality rate, special coronary heart disease (Anon, 2014d). Hypertension, diabetes and obesity are the high risk groups of coronary heart disease. Diet as a factor is affected the risk of coronary heart disease (Anon, 2014c).

Coronary heart diseases are caused by fatty material, such as saturated fat and trans-fat. The fatty material is made the vessel lumen became narrow. The blood pressure of coronary vessel increased (David et. al., 2012). The aging of blood vessel is loss the elastic and became hard and thick. It is caused not enough blood supply to the heart.

Omega-3 is a type of polyunsaturated fatty acid. It is included alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). World Health Organization suggested that 1-2 servings of fish per week and a serving need to provide 200-500 mg of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (Anon, 2014b). Omega-3 can control many of
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The relevant materials were researched in a number of databases, including PubMed, Science Direct, Medline (EBSCO HOST) and scholar in google. The keywords for searching were “coronary heart disease”, “omega-3”, “n-3” and “fish consumption”. The aim of this research is to identify the relationship between doses of omega-3 to the risk of coronary heart disease. Those papers took place in the last 20 years. The impact factor and citation index of those papers are 54.42, 14.948, 16.104 and 579, 350,
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