C.) The nurse would monitor for therapeutic effect of cyclophosphamide(Cytoxan) by continuing monitoring the blood pressure, respiratory rate, and temperature, ensuring they are within the range that the doctor set. You would also need to monitor complete blood count (CBC) and should be maintained at 2500– 4000/mm^3. Urinary output is important aspect when making sure the drug is in therapeutic range. You would want to monitor the urinary output to make sure it is in the range of 3000 ml/day so they are not developing the risk of hemorrhagic cystitis. Make sure to assess the cardiac and respiratory status for dyspnea, crackles, cough, weight gain, and edema. Pulmonary toxicity happens when prolonged therapy of drug. Another important thing to look for is bone marrow depression but monitoring for bleeding of gums, bruising, petechia, guaiac stool, urine, and emesis. …show more content…
The article “The effect of aprepitant and race on the pharmacokinetics of cyclophosphamide in breast cancer patients” shows that there is a significant difference between race. The purpose of this articles is to determine if the aprepitat influences pharmacokinetics of cyclophosphane. African Americans have significantly higher 2-dechloroethylcyclophosphamide concentrations, compared to Caucasians. Aprepitat is nausea and vomiting caused by chemotherapy. In conclusion, the race and aprepitant influences the use of cyclophosphamide. African Americans had an altered pharmacokinetics compared to
A new oral pharmaceutical drug for type- two diabetes had been approved for clinical use, it was called Compound 17392. Marketing companies instantly wanted to have prescribers adopt and sell the product and researchers wanted to further investigate previous reports of liver toxicity in patients. Now since paying patients to try new pharmaceutical drugs was an issue due to it appearing to interfere with clinical judgement and upholding the duty to do what is best for the patient, a new idea of furthering research for the drug came into play. The idea included recruiting a group of physicians who were in the top ten percent of prescribers for type-two diabetes. Following regulations put in place by researchers, these physicians were to enter eligible patients into the trial for Compound
The patient follows the doctor’s recommendation for completing blood work to ensure the medication is consistently within the therapeutic level. Therefore, the International Normalized Ratio (INR), prothrombin time
Case Study 2: What Race Has to Do with Breast Cancer Health disparities among difference race groups continue to be a public health concern. Some races have higher chances of being diagnosed to certain types of serious health conditions as opposed to others. In the United States, African-American women continue to have the highest rates of breast cancer, and at higher risk of being diagnosed at a more advance stage of breast cancer. Although, research has demonstrated that biology and genes can put an individual at a higher risk of cancer, researchers are now identifying outside factors that are affecting many more women. For example, an article released by Time “What Race Has to Do with Breast Cancer” social and culture factors, such as social economic status, can greatly determine the health risk outcome.
Pharmacologists and biotechnologists fusing genomics are presently spinning more towards a customized medicine to encourage the endorsement of new medications and in addition to propel the medication improvement process. "Pharmacogenomics inspects the acquired varieties in qualities that manage drug reaction and investigates the ways these varieties can be utilized to foresee whether a patient will have a decent reaction to a medication, a terrible reaction to a medication or no reaction by any
Since, the majority of African-Americans live in areas of drug involvement, they are more likely to be racially profiled and investigated. This has created an uneven ethnic ratio in prisons and produced stereotypes that affect children that prevent them from becoming abiding citizens.
Pharmacogenetics is the study of “inherited genetic differences in drug metabolic pathways which can affect individual responses to drugs, both in terms of therapeutic effect as well as adverse effects”. The field of pharmacogenetics led to the understating that drugs have varying effect on different races. Physicians now know many examples of such varying drug response in different races. One of which is difference in hypertension medicine response by whites compared to African
I will be assigned to a new patient next week, and I will make sure that I will know everything about all the medications the patient takes. That will be done in order to know what I am going to be administering and how dangerous it will be if any of them are administered incorrectly. I will make sure all preventable complications will not occur. In order to do that, I need to know the function of the medication and what they are really for based on the patient’s diagnoses.
African Americans African Americans are decedents of Africa that now live in America. They do not all carry the same cultural and ethnic beliefs though, and are a very diverse group of people. This diverse group does in fact have some overall similarities in their practices and beliefs. Some of the health beliefs that are similar are having a strong social support, caring about their community, using home remedies and faith healers for their health, and having fears of dying from cancer. Many turn to God and pray first and this can lead to a delay in getting professional medical help and treatment.
You will think, why them? they are more vulnerable to get into the "biggest company," the drug industry, because this is the only "job" that will always be practically available to whoever wants to get money to either survive or get an easy profit. The use of drugs is the biggest enemy of America. In The House I Live In, African Americans are mentioned all the time. According to the Drug Use and Abuse, "there is a variety of statistics indicating that the 'war on drugs
More interestingly, the drugs that are more common to be either produce, used or sold by African-Americans are given harsher penalties than drugs that are often used by the white population such as powder cocaine. Which has in turn, greatly contributes to the high incarceration rates among blacks, and the discretions of sentences given to blacks over other races. The heightened prison population has affected the taxpayers. Due to a
This study showed that there was a difference in African American and whites when it came to general health and ocular pain in which African americans had a slightly higher
According to Professor Amber Colbert, crack cocaine contains a slight amount of cocaine with various chemicals, including baking soda. Consequently, Michelle Alexander claimed a study that was published in 2000 by the National Institute on Drug Abuse, “NIDA reported that white students use cocaine at seven times the rate of black students, use crack cocaine at eight times the rate of black students, and use heroin at seven times the rate of black students” (Michelle Alexander;2011, Pg. 99). In spite of the study, the War on Drugs created mass incarceration. “When the War on Drugs gained full steam in the mid-1980s, prison admissions for African Americans skyrocketed, nearly quadrupling in three years, and then increasing steadily until reached in 2000 a level more than twenty-six times the level in 1983” (Alexander;2011, Pg.
Drug Kardexes were gathered and audited under certain criteria in order to identify potential risk areas in drug prescribing and administration, and also to provide ways in which these risks can be reduced or eliminated and reinforce drug management policies’ and guidelines. NICE (2002) audit cycle will be applied to this assignment to provide an acceptable framework (Appendix 1). Step 1: Preparing for Audit. The first step in the audit process is to identify which type of audit is to be carried out.
In January 2015, the death of a young First Nations girl sparked much controversy after her family withdrew chemotherapy in favour of traditional medicine. Eleven-year-old, Makayla Sault passed away after her battle with acute lymphoblastic leukemia. She had been given a 72% survival rate by doctors with a treatment planning involving intense chemotherapy, however, this aggressive approach landed her in the intensive care unit in the matter of 11 weeks. After the chemotherapy taking a major toll on the young girl’s body, both physically and mentally, and it came to the point that her parents were questioning if it was doing any good. Sonya Sault, Makayla’s mother, recalls her daughter telling her “I don't care if I'm going to die, I don't want
When interpreting concentration measurements, factors that need to be considered include the sampling time in relation to drug dose, dosage history, patient response, and the desired medicinal targets. The goal of therapeutic drug monitoring is to use suitable concentrations of difficult-to-manage medications to optimize clinical outcomes in patients in various clinical situations. Keywords: Drug monitoring, therapeutic; Pharmacokinetics Introduction Therapeutic drug monitoring is generally defined as the measurement of specific drugs at timed intervals in order to maintain a relatively constant concentration of the medication in the bloodstream. Monitored drugs tend to have a narrow therapeutic index, that is a ratio between the toxic and therapeutic doses of medications.