Danhong Injection Research Paper

Introduction
In the present, traditional Chinese medicine are wildly use worldwide for treatment several disease. The dried root of Salvia miltiorrhiza in the family of Labiatae known as Danshen in china is the one of traditional Chinese medicine popular drug in China that has a key role for cure various diseases either on its own or mixed with other herbs. It has been report that Danshen can be used for treatment coronary heart disease, cerebrovascular disease, Alzheimer’s disease, Parkinson’s disease, renal deficiency and other conditions of disease. There are many chemical compound that can be isolated from Danshen including the phenolic acids, terpenoids and others.
Most of traditional Chinese herbal medicines are administer by oral route which is the easiest route for administration of drug. However, for the immediate effects for treating patients such as cardiovascular or infectious diseases and for alleviating related symptoms the parenteral route is require. There are more than one hundreds types of herbal injections are approved by the China Food and Drug Administration for clinical use. DanHong injection is the drug that was prepared from the mixed of Salvia miltiorrhiza roots

DanHong injection will provided by Heze Buchang Pharmaceutical Co., Ltd. Each milliliter of DanHong injection will prepare from 0.75 g of Salvia miltiorrhiza roots Danshen and 0.25 g of Carthamus tinctorius flowers (Honghua). To prepare the herbal injection, Danshen and Honghua are mixed and extracted with water. After filtration and concentration under reduced pressure, the concentrated extract is precipitated with ethanol and centrifuged. The resulting supernatant is treated with active carbon, evaporated under reduced pressure to remove the ethanol, adjusted to pH 6.5–7.5, ultrafiltered, and sterilized. The finished product of DanHong injection is standardized to contain not less than 0.35 mg/ml concentration of tanshinol and protocatechuic aldehyde