Deep Vein Thrombosis Research Paper

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CARDDIOVASCULAR SYSTEM
DEEP VEIN THROMBOSIS
Anatomy and physiology
Vein is an elastic blood vessel that transports blood from all part of the body to the heart. Vein have four main types, which is pulmonary, systemic, superficial and deep vein.
Deep vein located deep within muscle tissue and typically located near the corresponding artery with a same name.
Deep vein thrombosis
Deep vein thrombosis (DVT) is pathology of cardiovascular system. It happens when the blood clotting in a deep vein of the blood vessel are clumps together and become thick.
Most of the affected areas are in the lower leg or thigh where the deep vein is located. They also can occur in the superficial veins and other part of the body.
Blood clots can cause obstruction
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The loose blood clots can block the artery in the heart and become pulmonary embolism (PE). A pulmonary embolism is dangerous conditions that can lead to fatal because of blood supplies from the heart to the other parts of the body are failed.
DISEASE CLASSIFICATION
Deep vein thrombosis can be classified to three categories which is idiopathic, acute and chronic.
Idiopathic deep vein thrombosis can characterized with usual condition acquired risk factors, such as obesity, trauma, cancer, or surgery. Acute deep vein thrombosis can be seen by pain and swelling. Usually acute deep vein thrombosis is occlusive where the clots already obstruct the blood flow. Chronic deep vein thrombosis can be label when there are no symptoms but it found by screening such as ultrasound doppler, CT Scan and blood
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It contributes to the formation of thrombi from the alterations in blood flow. It can be divided into two categories: primary or genetic and secondary or acquired (robins, deep vein thrombosis – ECAB).
MANIFESTATION
Some of cases of deep vein thrombosis have no symptoms, but doctors can observe the patient by looking to the sign of the symptoms.
Symptoms of the deep vein thrombosis are pain or tenderness in the leg. It will be warmth and heavy ache in the affected area.
Symptoms can be supported with the signs of the patient. Patient will have leg swelling and change in skin colours. The surface that effected may become dilated.
SIGNIFICANT LAB TESTS
D – Dimer test
D – Dimer test is a test to detect the formation of blood clots. Blood clots happen when the blood mix together with the protein, it will called fibrin. Another protein that called plasmin, break the clots apart. As the fibrin breaks down, levels of D – Dimer will increase.

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