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Dengue Fever Literature

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Introduction
Man is living in a quite hostile environment, and badly vulnerable to internal and external enemies. Of these numerous enemies, various kinds of microbial infections are of supreme importance. These microbial infections can be further sub-categorized on the basis of their etiological organisms, mode of transmission and organ system which is mainly affected by the injurious effects of microbial invasion. Dengue fever, also known as a break-bone fever, is one of these lethal microbial infections. Dengue fever is an ancient disease and many centuries ago its very first case was recorded in a Chinese medical encyclopedia in 9921. In the past dengue fever was considered as a tropical disease which was confined to a specific geographical …show more content…

Thus, the mosquitoes and the viruses were spread to new geographic areas. This “neo-colonization” of Aedes aegypti mosquito resulted in major epidemics of Dengue fever3. The first major epidemic of the severe and fatal form of the disease, known as dengue hemorrhagic fever, occurred in Southeast Asia 1950’s. In 1980’s a dramatic expansion of epidemic of Dengue fever and Dengue hemorrhagic fever occurred around the globe. Even, in the 21st century, the epidemic of Dengue fever (DF) and Dengue hemorrhagic fever (DHF) is the leading infectious diseases affecting tropical urban areas. It is estimated that incidence of DF and DHF is ranging from 50 million to 528 million per year 4. A study by WHO states that the actual statistics of Dengue cases are underreported and many cases are misclassified. The recent medical literature (2013) estimates indicates that 390 million dengue infections occur every year (with a 95% confidence interval 284–528 million). Another study which was conducted to determine the prevalence of Dengue fever reports that up to 3.9 billion people of 128 countries are prone to the infection with dengue virus4. The facts and figures regarding this fatal disease are …show more content…

Messina JP, Brady OJ, Pigott DM, Brownstein JS, Hoen AG, Hay SI. The global distribution and burden of dengue. Nature. 2013;1:140004.
4. Bhatt S, Gething PW, Brady OJ, et al. The global distribution and burden of dengue. Nature. 2013;496(7446):504.
5. Dick OB, San Martín JL, Montoya RH, del Diego J, Zambrano B, Dayan GH. The history of dengue outbreaks in the Americas. The American journal of tropical medicine and hygiene. 2012;87(4):584-593.
6. Crane G. Dengue haemorrhagic fever: diagnosis, treatment, prevention and control. Pathology. 1999;31(1):75.
7. Moulton SL, Mulligan J, Srikiatkhachorn A, et al. State-of-the-art monitoring in treatment of dengue shock syndrome: a case series. Journal of medical case reports. 2016;10(1):233.
7. Ben-Shachar R, Koelle K. Minimal within-host dengue models highlight the specific roles of the Immune response in primary and secondary dengue infections. Journal of the Royal Society Interface. 2015 Feb 6;12(103):20140886.
8. World Health Organization. "Comprehensive guidelines for prevention and control of dengue and dengue haemorrhagic fever."

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