Dengue Fever Research Paper

Dengue fever/dengue hemorrhagic fever is a dreadful disease or infection which is common in the sub-tropical and tropical countries. It is caused by any of the four closely related but genetically distinct arbovirus (DENV-1, DENV-2. DENV-3, and DENV-4) and transmitted between people by mosquitoes belonging to the species Aedes aegypti and Aedes albopictus. Arboviral infections are responsible for millions of diseases every year, most of these are due to dengue with its severe and often fatal syndromes of dengue hemorrhagic fever and dengue shock syndromes (DHF/DSS) which is a problem in more than 100 countries (WHO, 1996). The World Health Organization estimates 50-100M infections occur annually including 500,000 dengue hemorrhagic fever

Secretary Ubial earlier announced she was subjecting Sanofi’s anti-dengue vaccine, Dengvaxia, to further medical review to make sure it is safe for use among children. It can be recalled that when the vaccines were first introduced among its recipients, many side effects were noted. Thus, Senator Dick Gordon in one of his past privilege speeches in the house of Senate, expressed with strong conviction that the immediate procurement of the vaccines had turned the Philippines into the “number one guinea pig in Asia” and exposed Filipino schoolchildren to

The most common method used by the public to control mosquitoes is through the use of pesticides/insecticides. Pesticides are synthetic chemical solutions that have the ability to destroy the growth and development of the different stages in the life cycle or kill the adult mosquitoes. However, pesticides are dangerous to health. They are known to be carcinogenic. Pesticides also leave toxic residues in food products and are not easily biodegradable (Remia, et al, 2010). In short, pesticides both affect the target and non-target organisms, including humans and the environment (Pavel, 2007). Carica papaya Linn. (Family Caricaceae) is a tall (6-20 feet) and slender plant with a single trunk that has its origin in tropical America and has propagated to different tropical countries. Although some literatures consider it as a tree, the Hortus Third (dictionary of plants) identifies it as a giant herb because it does not produce a true woody tissue. The trunk is topped by an umbrella-like canopy of lobed leaves. In some parts of the world, papaya leaves are made into tea as treatment for malaria but the mechanism is not well understood and the treatment method has not been proven