Abstract Dermatomyositis (DM) is an autoimmune disease that presents with a wide range of classical dermatologic findings and proximal muscle weakness. Like other autoimmune diseases, multiple trigger mechanisms have been proposed in the pathogenesis of DM. They include infections, drugs, environmental factors and malignancy. Majority of the cases are idiopathic, but in approximately 15–30% of cases of adult-onset DM, an underlying malignancy is the cause of a paraneoplastic syndrome manifested as DM. We present a case of a 31 years old female who presented to us with a heliotrope rash, gottron papules, and shawl signs associated with proximal muscle weakness. She had no history of any constitutional symptoms of malignancy, however incidentally she was found to having a small palpable lymph node in her axilla. Later on screening she was diagnosed as having breast cancer. This case is a reminder that a common disease (breast cancer) may present with uncommon features (DM as a paraneoplastic syndrome), and physicians must consider malignancy as the underlying systemic process when an adult patient presents with DM. Key Words Dermatomyositis, paraneoplastic syndrome, Breast cancer Introduction Case Report …show more content…
She complained of gradual development of painful swelling and erythematous skin rashes over her face, neck, hands, chest and upper back. She also complained of gradual difficulty rising from sitting, climbing stairs and combing her hair. Symptoms progressively increased over time and she was unable to carry out her daily chores. She described symptoms of progressive dysphagia for solids. There was no history of weight loss, fever, and shortness of breath, oral ulcers, arthralgia, and
He has no Romberg 's sign. IMPRESSION: History of chronic inflammatory demyelinating polyradiculoneuritis. The strength and sensation of his extremities continues to improve after this, with no recurrence of symptoms from this with weaning off of Imuran. PLAN: Continue off of Imuran. Continue observation from a neurological standpoint.
After a few years, there was a tumor in her pituitary region. The tumor was secreting excessive amounts of growth hormone, casing symptoms to appear. She had enlarged hands and feet, coarsened, enlarged facial features, coarse, oily, thickened skin, and
Gait Markedly antalgic. Equivocal Romberg. DTRs 2+ in the upper extremities and knees, trace at the ankles. Labs/Studies CAT scan and C-spine are as noted
Anna Giles ' doctors are stumped. They have yet to diagnose the 17-year-old 's condition which makes her throw up 50 times a day. Her ordeal is so bad she has had to drop out of school. Her only wish is for someone to pinpoint what has afflicted her. Medical experts have ruled out a brain tumour, allergies, and even cyclical vomiting syndrome, the Daily Mail reported.
3, 4, 6b, 8, 10 Clinical signs include muscle weakness and atrophy, exercise intolerance and a paddling gait. Dysphagia and regurgitation are frequently seen with degeneration of the esophageal and pharyngeal muscles. Creatine kinase levels are elevated and there are bizarre discharges on EMG.
The clue thus accidentally obtained has been followed up by months of patient investigation, and has been thoroughly sifted. Today we lay before the world a story
Chapter 2 Activity #2 (1-10) 1. What is the English – language description for diagnosis code 696.1? Psoriasis 2. Describe the disease from question 1. Psoriasis- “is a skin disorder.
Pt. reports self-medicating with NSAID, but it was ineffective. She reported that what she’s experiencing makes it difficult for her to perform her usual activities. She stated that the same area where the rash is located started out as red bumps about 3-4 days, ago. She denies fever, chills, nausea and vomiting.
Dermatomyositis is an uncommon inflammatory muscular disease, which involves the degeneration of collagen, discoloration and swelling of the skin and underlying muscle. Dermatomyositis is known by it’s distinctive skin rash and muscle weakness. Dermatomyositis affects children and adults, but it usually affects children between the ages of five and fifteen, and it occurs in adults in their late forties through sixties. Dermatomyositis is also more commonly found in females than males.
Symptoms of skin cancer appear in certain places in the body such as redness in certain areas of the skin, other areas away from the natural redness of the skin.(6) Itching affects certain parts of the skin and it is one of the most important symptoms that show periods of intermittent.(6) continuous skin infections are one of the main symptoms of skin cancer, in addition to blue or red spots that appear on the skin.(6) Also symptoms of skin cancer in young people is having protuberances on the skin.(8) Skin cancer can be cured depending on the size of the tumor, its type, depth and location.(7)
Rosacea is a chronic, cutaneous, vascular skin disorder that causes redness to the face. It may also cause some swelling, tiny pink or red pimples and the presence of broken blood vessels may appear. Rosacea usually affects the cheeks, forehead, chin and nose. The cause of Rosacea is unknown today but there are several theories that cause the redness and flare ups in people with rosacea. These factors include spicy and hot foods, caffeine, alcohol, extreme temperatures, sun exposure, exercise, emotional stress, scrubbing or massaging the face, toiletries and some cosmetics.
The emergency room physician, David C. Lee, M.D., ordered medication, a series of diagnostic tests, and blood cultures, and he admitted Mrs. Adae to the hospital for further observation and testing, in order to rule out myocardial infarction and ACS. Dr. Lee listed "infectious etiology" in his differential diagnoses. Jennifer Bain, M.D., came on duty as an attending physician during the morning of June 29, 2006. Dr. Bain, an employee of UC, recorded her suspicion that Mrs. Adae 's chest pain was musculoskeletal. Dr. Bain noted that Mrs. Adae 's EKG, cardiac enzymes, and blood tests, with the exception of her elevated blood sugar, were normal.
Lupus is also a disease of flares, the symptoms worsen and you feel ill, and remissions (the symptoms improve and you feel better). (Wallace) Common symptoms of Lupus includes feeling very tired and having joint pain or swelling (arthritis), a fever, and skin rashes. The rash often happens after you have been in the sun. People with Lupus may suffer from mouth sores and hair loss.
The patient was diagnosed for polyps and multiple diverticula at the age of 68. The Patient suffers of painful osteoarthritis of both knees, shoulder hips. Patient?s mother deceased at the age of 79 from breast cancer and her father deceased at the age of 54 from heart attack. The patient noted with bilateral lower extremities edema, and claimed that she uses 2 pillows as a comfortable position to sleep,
Breast cancer has been around since the ancient times; the visible symptoms especially in the later stages were recorded by physicians (“History of Breast Cancer”). In 460 B.C, Hippocrates, father of medicine