It could be argued that morally, stem cells should not be used for regenerative medicine because stem cells need to be embryonic stem cells. These stem cells come from embryos from an in vitro fertilisation clinic whereby the fertilised egg was donated for scientific research purposes at the consent of the donor. (NIH Stem Cell Information Home Page, 2016) This can be morally incorrect as these embryos could have developed into foetuses and could have therefore been born and these may have potentially been people that would have been important to society. It can also be argued that the destruction of foetuses is against many religious beliefs and theses stem cells are morally wrong to
In this project, our aim was to capture spindle orientation in invaginating tooth placodes, and to determine whether the orientation of the spindles correlates with the stratification of the tissue. Therefore, this will help to determine whether the mechanism of delamination is driven by oriented cell division. Animal husbandry and embryo isolation were carried out following procedure under the UK Home Office Animal Act 1986. CD1 wild type mice were used, and embryos were collected at E11.5. Pregnant mice were killed by cervical dislocation, and the uteri dissected using No.5 forceps and placed in culture medium, consisting of Dulbecco’s modified Eagle’s medium (DMEM) and Penicillin streptomycin.
Now mutations of this gene are controlled by inserting the IPTEN gene which is discovered in model organism Dicyostelium discoideum. This gene have the ability to suppress the mutations that are found in PTEN gene. Methodology: • DNA extraction • Gene isolation by using restriction enzymes • Induced PTEN mutation in Mice to induce Cowdin syndrome • Insertion of IPTEN gene in
Clones require a somatic cell nucleus and a fertilized egg cell sans nucleus. The genetic scientists in Jurassic Park obtained dinosaur DNA from blood in fossilized mosquitoes. Presumably, the genetic material came from white blood cells, considering that red blood cells have neither a nucleus nor DNA. To clone the
They believe that messing with Gods will is erroneous and this will cause problems to arise between different groups who oppose the opinion therefore stem cell transplants are better off avoided and only tested in the laboratories but not performed on humans. In conclusion, stem cell research does have lots of disadvantages that outweigh the advantages and it is a good reason to not use it as an approved procedure currently but attempt to study it more, develop and it improve it so that at one point in the future it may become more ethical and acceptable than it is at this
Globally, scientists are turning to stem cell research as the most promising step to curing many of the harshest diseases and conditions including cancer, Alzheimer’s, stroke, paralysis and many more. Stem cells are useable as a replacement for damaged cells because of their self renewing properties. Their form allows them to act as other types of cells and regenerate as a substitute for the affected cells or as a way of testing new medications. Stroke related disabilities alone account for more than 1.2 million people and millions more are impacted by other cell related disabilities making stem cell research an essential pursuit in order to make strides in medicine (Cunningham 368). However, the success of researchers has been limited as the
During the 1970s it became possible to introduce exogenous DNA constructs into higher eukaryotic cells in vitro. Mammalian (germline) trans genesis was first achieved in the early 1980s. The model used in this study was mice. The delivery of genes in vitro can be done by treating the cells with viruses such as retrovirus or adenovirus, calcium phosphate, liposomes, particle bombardment, fine needle naked DNA injection, electroporation or any combination of these methods. These are the powerful tools for research and have possible applications in gene therapy.
Can it become fatal in some cases?.It all mainly depends on how our system works and how our immune system responds to the situations that arise (3). The main role of fetal cells and maternal cells and their total response to each other in disease or health has not been completely identified. The future works on this topic include:1. understanding the maternal and fetal alleles,2.reseraching on exactly how the foetal cells affects the maternal tissues and3. measuring the fetal and maternal immune cell interactions(6). Several new techniques have been identified like: bioluminescent imaging for in vivo FMC cellular trafficking using nano particle