ipl-logo

Doege-Potter Syndrome Case Study

1091 Words5 Pages

Doege-Potter Syndrome, cause of non-islet cell tumor hypoglycemia, the first case report from Nepal. Abstract Doege–Potter syndrome (DPS), a paraneoplastic syndrome, presents as a hypoinsulinaemic hypoglycemia from the ectopic secretion of insulin-like growth factor II (IGF-II) from a solitary fibrous tumor which may be intrapleural or extrapleural in origin. We report a case of severe hypoglycemia in a 68-year old lady initially admitted for resection of left sided solitary fibrous tumor of pleura (SFTP). Investigation revealed true hypoglycemia and DPS was diagnosed. The tumor was completely resected and the patient made a full recovery with no further hypoglycemic episodes. This is probably the first case of SFTP with DPS reported from …show more content…

The admission prior to surgery was complicated by hypoglycemia, leading to cancellation of the surgery. Surgery was postponed until an endocrinology evaluation was completed. There was absence of any underlying endocrine pathology. The administration of hypoglycemic agent was ruled out. The patient was clinically Whipple’s triad positive suggesting true hypoglycemia. He was also found to have normal thyroid and adrenal function insulin level of <3 mU/L [3.0-25.0 mU/L]Serum C-peptide level was below 0.05ng/ml which was very less (Ref: 0.81-3.85 ng/ml). Anti-insulin antibody was …show more content…

Kalebi AY, Hale MJ, Wong ML, Hoffman T, Murray J. Surgically cured hypoglycemia secondary to pleural solitary fibrous tumour: case report and update review on the Doege-Potter syndrome. Journal of cardiothoracic surgery. 2009 Aug 18;4(1):45. 2. Daughaday WH, Kapadia M. Significance of abnormal serum binding of insulin-like growth factor II in the development of hypoglycemia in patients with non-islet-cell tumors. Proceedings of the National Academy of Sciences. 1989 Sep 1;86(17):6778-82. 3. England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura: a clinicopathologic review of 223 cases. The American journal of surgical pathology. 1989 Aug 1;13(8):640-58. 4. Gold JS, Antonescu CR, Hajdu C, Ferrone CR, Hussain M, Lewis JJ, Brennan MF, Coit DG. Clinicopathologic correlates of solitary fibrous tumors. Cancer. 2002 Feb 15;94(4):1057-68. 5. Santos RS, Haddad R, Lima CE, Liu YL, Misztal M, Ferreira TD, Boasquevisque CH, Luketich JD, Landreneau RJ. Patterns of recurrence and long-term survival after curative resection of localized fibrous tumors of the pleura. Clinical lung cancer. 2005 Nov

Show More
Related

  • Abigail Ugly Research Paper

    393 Words  | 2 Pages

    After a few years, there was a tumor in her pituitary region. The tumor was secreting excessive amounts of growth hormone, casing symptoms to appear. She had enlarged hands and feet, coarsened, enlarged facial features, coarse, oily, thickened skin, and

    Read More

  • 2-Piriformis Syndrome: A Case Study

    398 Words  | 2 Pages

    However, this diagnosis can be excluded to some extent where the case has swelling in the

    Read More

  • Cushing's Syndrome Research Paper

    917 Words  | 4 Pages

    Cushing’s Syndrome is a disease that involves an excess of the Adrenocorticotropic hormone (ACTH) from the pituitary gland, most likely because of cancerous cells (Helm). This causes an excess of cortisol to be made in the adrenal gland which creates the symptoms known as Cushing’s Syndrome. This can also be caused by a tumor on the adrenal gland which causes an overproduction of cortisol (Helm). Cortisol is a steroid hormone which helps regulate blood sugar as well as aid in the metabolism of protein, fat, and carbohydrates.

    Read More

  • Case Study 1: The Endocrine System

    1100 Words  | 5 Pages

    He had a pituitary tumor removed, an operation on his knee and metal pins placed in his hips. And his jaw was split into fine pieces in order to be expanded because of the acromegaly. Doctors Notes • Swelling of right knee. • Ulcerated sores on lower left leg. • Abnormal hormone levels.

    Read More

  • Jittery Case Studies

    1603 Words  | 7 Pages

    The normal glucose is 30- 90. The baby result was 54. This lab result was normal and was done because the baby was jittery at birth. Signs of hypoglycemia in a newborn are jitteriness and hypothermia. The baby also had a normal temperature but it was on the lower end of normal.

    Read More

  • Addison's Disease Research Paper

    570 Words  | 3 Pages

    Addison’s Disease is a rare disorder where the adrenal glands, that’s located directly above the kidney, does not produce enough of the cortisol hormone. Addison’s disease can be separated into 2 sub conditions, primary adrenal insufficiency and secondary adrenal insufficiency. People with primary adrenal insufficiency suffer from both a lack of the aldosterone hormone and the cortisol hormone the adrenal glands produce. People with secondary adrenal insufficiency only suffers with a lack of cortisol. The disease is found in every age group and both sexes.

    Read More

  • Dumping Syndrome Research Paper

    547 Words  | 3 Pages

    low blood sugar level). It occurs anywhere between 1 to 3 hours after eating. The hypoglycemia associated with LDS causes symptoms such as: • Tremors • Sweating • Hunger • Palpitations • Sweating • Fatigue • Fainting • Confusion • Aggression LDS reactive hypoglycemia occurs due to a rapid absorption of glucose from the small intestine and a responsive hyper-secretion of insulin with stays elevated for a period longer than usual. GLP-1 is thought to play a crucial role in LDS as it is a potent anti-hyperglycemic hormone a. It often found to have an elevated response in patients who have had operations that speed up gastric emptying and causes increased insulin secretion, further compounding hypoglycemia.

    Read More

  • 22q11.2 Deletion Syndrome

    658 Words  | 3 Pages

    At present it is treated symptomatically and therapeutically. It is important to identify which of the features that the individual with 22q11.2DS presents. Potentially serious defects such as cardiac abnormalities can be spotted early and be corrected with surgery. Similarly, a hypoplastic thymus can be replaced with a transplant from a donor to restore optimum immune function. If infections are still contracted, then antibiotics can be taken.

    Read More

  • Pushing's Syndrome Case Studies

    1179 Words  | 5 Pages

    c) A 50 yrs. Old lady admitted in hospital with hyperglycemic coma. High blood glucose also known as hyperglycemia, most important health difficulties in the peoples with diabetes in excess of time. Several factors can be contributed to hyperglycemia, as well as eating more carbohydrates than normal and being less physically active than normal. Regular blood sugar testing is crucial for people with diabetes, for the reason that several people do not impression the symptoms of high blood sugar.

    Read More

  • Mesothelioma Research Paper

    1159 Words  | 5 Pages

    In its initial stages, mesothelioma does not have numerous manifestations, whether it is in the mid-section (pleura) or the guts (peritoneum). At the point when indications do create, they are frequently brought

    Read More

  • Arthroplasty Case Study

    528 Words  | 3 Pages

    He has pain with sitting, standing, walking, and lying down. He has had physical therapy and chiropractic care with only transient relief. He is taking Motrin, Norco, and Neurontin for pain. Based on the progress report dated 09/19/16 by Dr. Dhillon, the patient was last seen on 08/15.

    Read More

  • Neurofibromatosis Research Paper

    831 Words  | 4 Pages

    These tumors are constantly growing and most are inaccessible to surgical removal. NF could also cause malignant and bone abnormalities, vascular abnormalities, and pain. Neurofibromas are the most common benign tumor of NF and usually grow on or just under the skin. Sometimes these tumors can occur in deeper areas of the body. Studying NF1 is difficult in 60 % of all cases because of learning disabilities caused by the disorder (Kalamarides et al, 2011).

    Read More

  • Infant Blood Workaround Case Study

    1333 Words  | 6 Pages

    Due to this, we had to send a blood sample down to lab stat. Because the mom did not want to breast feed, we gave the infant 15 mL of formula. The next time we took at blood glucose, it was up to 40, so no farther action was

    Read More

  • Type 1 Diabetes Research Paper

    610 Words  | 3 Pages

    Diabetes is a diseases characterized by hyperglycemia resulting from defects in insulin secretion or insulin action, sometimes both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of various organs, like eyes and kidneys, can also cause problems with blood vessels.. There are three main types of diabetes: type 1, type 2, and other specific types which we classify as one type. There is important and the most common type of diabetes is prediabetes, that is why we classify this type as a first one. It is a condition whenever blood glucose level is very high and higher then normal level but not high enough for be type 2 diabetes.

    Read More

  • Type 1 Diabetes Essay

    589 Words  | 3 Pages

    Synthesis of glucose takes place in the liver and it is then transferred to the blood to be supplied to all parts of the body for fueling cellular processes. For using glucose as a fuel, insulin is needed for getting the glucose into the cells (Eiselein & Schwartz). The specialized cells in the pancreas make insulin which is a hormone responsible for regulating blood glucose. It stimulates the removal of glucose from the blood and assists in storing it in liver, muscle and fat cells as energy. Often enough insulin is not made by the body or the cells stop responding to insulin.

    Read More

More about Doege-Potter Syndrome Case Study

Open Document