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Essay On Blood Clots

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THROMBOSIS
When a blood vessel is injured, the cells of your blood bond together to form a blood clot. The blood clot helps you stop bleeding. Blood clots are made of a combination of blood cells, platelets (small sticky cells that speed up the clot-making process), and fibrin (protein that forms a thread-like mesh to trap cells). Doctors call this kind of blood clot a “thrombus.” Blood clots are good when they help seal a cut to stop bleeding. But sometimes, a blood clot can form when it is not needed. This type of blood clot can cause health problems or even death. A blood clot that forms in a major vein deep inside your body is called a Deep Vein Thrombus (DVT). Most DVTs occur in the blood vessels of the lower legs or thighs.
Artificial …show more content…

The complement system is regulated by complement control proteins, which are present at a higher concentration in the blood plasma than the complement proteins themselves. Some complement control proteins are present on the membranes of self-cells preventing them from being targeted by complement.
The coagulation phase begins about thirty seconds after the initial injury. It involves a complex sequence of events that ultimately leads to the activation of fibrin form fibrinogen. There are two separate clotting pathways, the intrinsic and the extrinsic. These eventually join together to form the common pathway.
The adsorption of the components of the contact system facilitates the activation of the intrinsic pathway of coagulation. This results in the formation of thrombin which converts fibrinogen to fibrin monomers. The thrombin also promotes platelet aggregation. The fibrin stabilizes the platelet aggregates forming a platelet-fibrin thrombus. The formation of this thrombus on the device is bad as it can block the flow of blood to crucial organs including the heart and it can have fatal consequences. Thrombus formation on artificial devices is the result of both platelet activation and

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