The heart is a muscular organ that pumps blood throughout the body. The human heart is con shaped and has the size of a closed fist. In accordance to that, a bigger person has a bigger fist and therefore a bigger heart. Moreover, it is the only involuntary striated muscle that is consisting of four chambers: two upper chambers “atria” and two lower one “ventricles”, where the right side of the heart is separated from the left side by an inter-ventricular septum, and they are connected by pulmonary arteries and pulmonary veins.
Although the human heart is the first organ that starts development, it takes several stages to be formed (figure1):
• First stage: Formation of the primitive heart tube: That is done after the fusion of endocardial
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• The apex (inferior tip of the heart) sits on top of the diaphragm (the muscle that helps in breathing).
1.1 Anatomy of the Heart
1.1.1 Serous Pericardium
It is composed of two layers (figure 3):
• The outer layer called the Parietal layer and it stuck tightly to another layer called Fibrous Pericardium which is made of tough dense connective tissue that holds the heart in his place and prevents from over filling of blood.
• The inner layer called the visceral layer and it stuck directly to the heart itself, forming the pericardium (the outer layer of the heart).
The cells of the serous pericardium secrete a protein rich-fluid that fills the space between the parietal and visceral layers. The cell’s secretion help on lubricating the heart, preventing heart friction with its surrounding organs during contractions, holding the heart inside the chest and maintaining a hollow space for the heart to expand into when it is full of blood.
1.1.2 Structure of the heart wall
The heart wall is composed of 3 layers (figure 3):
• Epicardium: As mentioned before, the epicardium is at the same time the outermost layer of the heart wall and the inner wall of the pericardium (visceral layer). It protects and lubricates the
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• Systole is when the cardiac muscle contracts to push out the blood from the chamber they are in it. During ventricular systole the blood pressure increases in arteries.
• Diastole is when the cardiac muscle is relaxed allowing allow the chamber to fill with blood. During ventricular diastole the blood pressure decreases in arteries.
This leads to conclude that the higher blood pressure is the systolic pressure (for example 120 mmHg), and the lower blood pressure is the diastolic pressure (for example 80 mmHg).
1.2.2 The Cardiac
The Pintails heart is like a mammals consisting of four chambers, two ventricles and two atria. The left ventricle pumps blood to all major organs in the body and throughout the rest, only excluding the lungs. This causes the left ventricle to be larger and more muscular. The lungs are fed blood from the right ventricle, which is the only the only function of that ventricle. The oxygenated blood coming from the lungs is fully separated from the oxygenated blood coming from other parts of the body.
Systolic and Diastolic Heart Failure Heart failure occurs when the heart cannot pump enough blood for the body due to a weakened or damaged heart. The heart 's pumping action moves oxygen-rich blood as it travels from the lungs to the left atrium, then on to the left ventricle, which pumps it to the rest of the body. The left ventricle supplies most of the heart 's pumping power, so it 's larger than the other chambers and essential for normal function. (American Heart Association). In left-sided or left ventricular heart failure, the left side of the heart must work harder to pump the same amount of blood.
The major conclusion of the experiment is that Zebrafish heart regeneration is a result of pre-existing cardiac muscle cells, not from a distinct parent cell. Introduction The problem being examined is not being able to know the definite source of recently developed cardiomyocytes in Zebrafish heart regeneration. The hypothesis is that previous cardiomyocytes originate from progenitor cells. It is essential to understand that
It has an inner (visceral) layer which is next to the lung and an outer (parietal) layer that covers the chest wall. The two layers slide over each other as we breath and membranes in the lungs
Therefore the cardiovascular system relies on a correctly functioning mitral valve, in order to stay
The cardiovascular system is broken down into two circulatory pathways: systemic circulation and pulmonary circulation. Systemic circulation carries oxygenated blood away from the heart to the body or organs, and then returns deoxygenated blood to the heart. Whereas the pulmonary circulation transports deoxygenated blood from the body or organs to the right side of the heart to the lungs and return oxygenated blood to the left side of the heart (Marieb, Nicpon, and Hoehn, 2013). The cardiac cycle consists of an ejection and a filling stage: systole and diastole, respectively. During the diastolic phase the heart ventricles are relaxed as the heart fills with blood, and blood pressure is the lowest; during the systolic phase the heat ventricles contract and pump blood out of the arteries, and blood pressure is increasing.
Our hearts serves as biological pumps responsible for pumping blood through blood vessels to body tissues. The hearts pumps blood by undergoing cycles of contraction (systole) and relaxation (diastole) in what is referred to as cardiac cycles. Each cardiac cycle, therefore, represents one heart bit. The number of heart bits per minute is referred to as the heart rate. The pumping mechanism of the heart is dependent on the pressure differences created in the chambers of the heart following the contraction and relaxation of heart muscles.
The cardiac cycle is the coordination of the filling and exhausting of blood by electrical signals that cause the heart muscles to contract and unwind. The contraction of the heart is directed by a nerve drive that goes from the SA node to AV node to AV group to Purkinje fibers to the myocardium. Amid the cardiac cycle, the heart contracts by means of systole, pushing blood out of the heart, and unwinds through diastole, filling the heart with blood. Cardiomyocytes, or cardiac cells, are striated and are in charge of the pumping of the heart; they are the main muscle cells with intercalated plates. The heart's inner pacemaker controls and times the thumping of the heart by means of electrical signals.
Scientists believed that the right ventricle had little to no role in cardiac mechanical function. However, as scientists did more research they found that the right ventricle played an important role in cardiac function. The scientists conducting this research wanted to better understand the structure and function of the RV. They studied the anatomical structure of the RV and discovered that RV has a more elaborate anatomical structure than that of the LV. The RV fibers are composed of several layers of muscle, giving the RV its shape.
“An average heart has four chambers; two upper, called the atria and two lower, called the ventricles. The right side of the heart receives blood that is returning from the body. This oxygen-lacking blood arrives in the right atrium, where it is pumped into the right ventricle.” (Blaser). This is the structure of the heart, an organ every person in the world has, and that so happens to be the most important organ in an organism’s body.
Introduction This essay will reflect on my personal experience, skills, and knowledge gained from my studies and practice of undertaking blood pressure (Bp) whilst completing my professional placement. Bp may be defined as a force of blood against vessel walls in the body, consisting of systolic and diastolic pressure measured in millimeters of mercury. (Waugh and Grant, 2016) Systolic pressure occurs when the hearts left ventricle contracts and forces blood into the aorta causing a heightened atrial pressure, while diastolic pressure refers to complete cardiac diastole, this is when the aortic valve closes and pressure is at its lowest between beats, blood moves into smaller corresponding vessels and the heart rests.
It will not be until 1999, when the first complete blood vessels were grown outside of the body at Massachusetts Institute of Technology. The technique consisted of obtaining smooth muscle cells from the medial layer located in the aorta of a six-month-old pig. A substantial amount of these cells were pipetted over the outer surface of a tubular scaffold, which was mainly composed of polyglycolic acid (PGA). This polymer is also known to be degradable and used in sutures. Time after the seeding period, each individual scaffold was placed in a bioreactor, also known as a growth chamber.
Most often the blood pressure is tested by a healthcare worker using a gauge, sensor, or a stethoscope and they measure the systolic pressure (blood pressure when the heart beats) and the diastolic pressure (blood pressure between heartbeats). The reading is systolic over diastolic, for example, 120/80. The heartbeat
The measure of the changing of fluid pressure in the circulatory system is defined as blood pressure. Blood pressure is the measured as the force per unit area applied on the walls of the blood vessels, especially the arteries. Systole is the peak pressure produced by the contraction of the left ventricle, which is followed by a fall in pressure, termed diastole, when the left vernicle relaxes in preparation for the next contraction. The standard blood pressure is measured at 120/8 mmHg, where the top represents the systolic pressure and the bottom represents the diastolic pressure.
The heart is pretty small because it is around the same size as a persons fist. The heart has four chambers on the inside (internal chambers) and these chambers accumulate blood and pump the blood to