Eurycoma Essay

1. INTRODUCTION (1)

Eurycoma longifolia (commonly called tongkat ali or pasak bumi) is a flowering plant that are widely used for citizen from Indonesia, Malaysia, and, to a lesser extent, Thailand, Vietnam, and Laos. In folk medicine of the South East Asian region, the root of the plant has been used and in modern times, it has been used as supplements with similar functions, as well as food and drink additives.

2. PLANT CLASSIFICATION & NOMENCLATURE (1)

a. Plant Latin name

: Eurycoma longifolia

b. Classification of the plant

Rank Scientific Name and Common Name

Kingdom Plantae

Order Sapindales

Family Simaroubaceae

Genus Eurycoma

Species Eurycoma longifolia

c. Local name: Tongkat Ali.

d. Vernacular names:(2)

Malaysia Tongkat ali, Penawar pahit, Bedara pahit, Lempedu pahit, Payung ali, Tongkat baginda, Muntah bumi, Petala bumi.

Indonesia Babi kurus (Java), Tungke ali (Sumatera), Pasak bumi, Bidara laut.

Thailand Phiak, Tung saw.

Laos Tho nan.

Cambodia Antong sar, antoung sar.

Vietnam Cay ba binh.

3. MORPHOLOGY & CHARACTERISTIC OF THE PLANTS(3)

This tree can achieve maximum height of

longifolia extract affects male infertility bystopping AHS expression, which indirectly increases insulin sensitivity and testosterone levels in accordance with our previous findings. Stefan had reported that AHS has been linked to insulin resistance and diabetes. The insulin receptor is a disulfide-linked heterotetrameric protein complex have two hormone-binding α subunits and two signaling β subunits containing tyrosine kinase activity. Insulin binds to this receptor located on the surface of insulin responsive cells, leading to the activation of the tyrosine kinase and subsequently the autophosphorylation of β subunit in order to activate the function of insulin toward the physiological function.The phosphorylated form of AHS acts as a natural competitve inhibitor of insulin, which blocks both activities, potentially contributing to the development of type-2