Fenugreek Research Paper

Fenugreek also known as Helba in Arabic, Methi in Hindi, Shanbalile in Persian or for its scientific name Trigonella Foenum-graecum L. It is aromatic 30-60 cm tall annual herb belonging to the Leguminosae family broadly developed in different part of the world such as, India, Mediterranean countries, North Africa, Saudi Arabia and Southern Europe. Their plant produce a small yellowish-white flower containing seeds. It's seeds and leaves are used not only for spice used in food or flavoring but also as a medicinal herb. The effective therapeutic part of the plant is their dried ripe seeds, which contains similar progesterone and, or estrogen effect. Fenugreek seeds contain various possible Active ingredient e.g. flavonoids, fenugreekine, steroids,

They mostly produce steroid hormones and haploid female gametes (Ova). The Hypothalamus secrete gonadotropin-releasing hormones (GnRH) and its function to stimulates the pituitary glands to secrete Follicle-Stimulating hormone (FSH) and Luteinizing hormone (LH). FSH is responsible for early maturation of ovarian follicles. As the follicle increase in size and estrogen hormone is secreted. When estrogen is produced, it inhibits farther secretion of FSH and stimulates the releasing of LH. The ovulation occurs when the level of LH in the blood is high concentrated. Ovulation influence the follicle cells that stays in the ovary and its transformation into corpus luteum. Corpus luteum release a high amount of progesterone and few estrogen hormones which lead to inhibition of both FSH and LH. Without FSH and LH corpus luteum secretes less progesterone and estrogen and FSH and LH is no longer inhibited and the cycle repeated. This cycle is called Hypothalamo-pituitary ovarian

Normalize the deranged level of phosphoenol pyruvate, carboxykinase and pyruvate kinase enzymes and inhibit the intestine disaccharides by galactomannan . Fenugreek provide a good effect on intestinal and renal disaccharide activity in streptozotocin (STZ) induce diabetic rats through enhance maltase activity reduction during diabetes. In human, steroids and 4-OH-Ile present in fenugreek have a hypoglycemic effect by stimulating glucose-dependent insulin secretion from beta cell and by inhibiting two enzymes involve in metabolic of carbohydrates in intestine they are alpha-amylase and sucrose