If you had seen Frederick Novy at the University of Michigan between 1888 and 1933, you might have dismissed him as an eccentric scientist in a threadbare suit and mismatched coat, careening across campus on his bicycle, oblivious to much except the thoughts in his head. You could have even shrugged at the way he holed up in his dim and cramped lab until late at night, poring over data and experiments, almost to obsession.
But to do so would be to miss his extraordinary contributions to medical science and the U-M Medical School at a time when medicine was lacking certainty and authority. As a student, Novy questioned treatments he was taught, such as bloodletting, cupping and the application of leeches. In his student notebooks and lecture notes, now archived at U-M’s Bentley Historical Library, he observed that there were no laboratory exercises to teach students how to investigate the cause of disease. To him, adding laboratory science would “lead to the uplifting of medical education that was needed.”
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He became the leader of a new breed of physician: academic researchers who did not practice medicine. He would engineer new lab equipment to better see organisms on a cellular level, at a time when some of his U-M colleagues didn’t even believe in germ theory. And although he would tout the importance of scientific experiment for its own sake, without worrying about pragmatic application, his work would have profound effects on a deeper understanding of how germs and bacteria behave, leading to reduced incidents of dysentery, cholera, tuberculosis and
Doctors and scientist became desperate to test the cell
Doctors thought, since patients were receiving quality treatment they thought it was okay to experiment on them in return. The doctors at Hopkins took advantage of their patients because they knew they were uneducated and they wanted to advance their personal
The fervent ideal-searching that entails scientific research is an endeavor that encompasses not only intellectual bounds but also the mental and emotional fixtures present in the mind of a scientific pioneer. Mere thoughts and notions become materialized tools and obstacles, and the journey that takes place within becomes the foundation by which scientific theory is ascertained. Wielding thoughts as stepping stones is crucial to the duty of the scientist, and even a degree of uncertainty must be harnessed for success and improvement. In this excerpt from The Great Influenza, John M. Barry pieces together a passionate study on the character of scientific research through the artful use of rhetorical strategies including syntax, hypothetical
One of the major surgeries of note that took place in the United States in 1809 was the ovariotomy of a Kentucky surgeon. Expected twins came to naught and a 20 pound ovarian tumor in Jane Crawford’s protruding belly needed to excised. Performed on Dr. McDowell’s kitchen table, before anesthesia, before sterilization, Mrs. Crawford sang hymns, lost 20 pounds and went on to live another 31 years. Medicine in the United States during the Civil War era was almost at a standstill. There were some medical advancements to note: 1846 Chloric ether gas (Chloroform) was used regularly to anesthetize patients before tooth extractions and surgeries.
There, in 1904, he received a medical degree. in 1907, Oswald Avery began working at a laboratory at Hoagland Laboratory in Brooklyn, after being distraught in not being able to optimally help some of his patients. This was the first privately endowed bacterial research laboratory in the United States. There, Avery earned the nickname “The Professor”, or more commonly, “Fess”. He worked on many strains of bacteria, and worked on the bacteriology of yogurt as well as tuberculosis.
Then he sent it down the hall to scientist who had been trying to grow tissue for years and years” (Zielinski, 2010, p.2). Back then it was common for doctors to take samples from their patients (Barone, 2014, p.1). Southam filled a syringe with HeLa cells and injected them into cancer patients. He told them he was checking their immune system. Within hours their forearms grew red and swollen.
In the passage from John M. Barry’s The Great Influenza, Barry makes us of an extended metaphor of scientific research as an unexplored wilderness, a motif of uncertainty, a comprehensible diction and admiring tone, and bookended explanatory paragraphs to characterize scientific research as a courageous pursuit to bring order from chaos. Throughout the piece, Barry develops the metaphor in a fashion which closely parallels the steps of the scientific method, giving the reader a better understanding of the work of scientists. In an effort to promote scientific research to the general public, he focuses on its positive aspects and the character traits of scientists. In order to appeal to a wide audience, Barry uses an extended metaphor to compare the seemingly abstract and unreachable concept of scientific research to the mentally attainable image of pioneers settling a virgin wilderness.
The scarcity of resources and practiced physicians that characterized medical care of the era was increasingly evident in war times, ultimately displaying a growing necessity of effective treatment that could accommodate the masses of Union and Confederate soldiers. Gangrene and Glory: Medical Care During the American Civil War by Frank R.Freemon illustrates the shortcomings of ineffective health care and revolution of surgical practices, highlighting the fields profound impacts on the dynamism between Union and Confederate army forces. This source draws evident separations of American medicine in the 1850’s and wartime medical treatment demonstrable through the comparisons of mortality rates of soldiers as well as depicting the evolutions of surgery. The most widely infamous of surgical technique was the practice of amputation (in which surgeons would perform when arterial damage of a limb was irreversible), however the use of anesthesia such as chloroform/ether as well as progressions in plastic surgery and open chest surgery also contributed to the refinement of medicine.
On September 16, 1862, Daniel M. Holt M.D. wrote to his wife, “Shortly [we encountered] a rebel with his brains blown out, arms extended, and eyes protruding from their sockets, some not yet dead but grasping the few remaining breaths away in utter unconsciousness, others mortally wounded calling for water knowing that eternity was separated only by a hair’s breadth… I have seen what I never once expected I should see.” Dr. Holt of the 121st New York Army further describes the carnage and horror that he and countless other Civil War surgeons encountered in letters and journals written during his experience in the war. While working during a time described by Surgeon General William Hammond as “the end of the Medical Middle Ages,” it was inevitable
Being able to identify unknown microbes from systematic testing is what makes the field of microbiology so important, especially in infectious disease control. Using the testing procedure laid out by the microbiology field we are able to identify unknown bacteria present in our everyday lives, and along the way learn a lot about their characteristics that separate them from other types of bacteria. Being able to do this is vital in order for us to understand why microbes are present in certain places, how they are able to grow and what restricts their growth, that way they can be combatted if necessary. These techniques for determining unknowns are also important for isolating and testing infectious disease microbes in order to prevent spreading. Another important aspect of being able to identify unknown microbes is the
This caused an influx of new medical practices in the years to come. This was due to the fact that many people were dying in numbers larger than some populations, but the methods at hand were not sufficient. With the emergence of the first teaching hospital at the University of Pennsylvania and beyond, the opportunity to learn about diseases and how to treat them was available. This was entirely due to the fact that there was a demand for this; a need, and with comes a response.
After opening his own practice, he began to teach anatomy at the Chicago Medical School. Also, within his own office Williams practiced the sterilization process on germ transmission and prevention that was brought about by Joseph Lister and Louis Pasteur. After opening his own practice, there was an issue where blacks were not allowed to work in hospitals. Feeling as though he had to find a solution to the problem that they were facing, Williams decided that he would fund a hospital that allowed blacks to work and practice medicine.
Stephen Hawking declared, “Scientists have become the bearers of the torch of discovery in our quest for knowledge.” Since the beginning of time, humans have been searching constantly for answers and knowledge about the world around them. Scientists have brought it upon themselves to be the discoverers of the human race. John Barry wrote his account during The Great Influenza of 1918 when millions of people were dying and solutions to the sickness were being sought out after by the scientific community. In his account of The Great Influenza of 1918, John Barry implements scientific diction, frequent repetition, and unique symbolism to demonstrate the difficult journey of scientific research.
In Philadelphia 1973 early August, a robust and fatal disease had emerged through the garbaged pavement roads and city ‘sinks’. Dr. Hugh Hodge was one of the first to encounter the deadly disease, and it taking the life of his daughter days before meeting with a new patient with the same grotesque symptoms. Hugh and his colleague Dr. John Foulke cautiously cared for Catherine LeMaigre, reciting and reviewing previous documents that would provide treatments for such a harmful, painful disease. The tactics both the Doctor’s had used didn’t help with Catherine ’s well being, and thus astonishing them since they haven’t ever seen prestigious methods shot down.
To Graduate Committee Admission of Biochemistry and Cell Biology Program of Rice University: My inclination to study biology comes to me since I was little boy. I always found amazing the capabilities of living beings and mechanisms that allow life, development and evolution of organisms. Particularly interesting were my first approaches to microbiology in early classes in high school. My fascination by biological sciences was such that it led me to win the National Biology Contest held in Cuba, my native country in 2004. This was one of my first academic achievements in my short career and allowed me to directly enter the best pre-university school in my country.