Antioxidants In Microorganisms
Free radicals are continuously produced in our body, due to oxygen utilization and results in the generation of a series of reactive oxygen species and non-free radical species. Reactive oxygen species are highly reactive and can easily react with most biological molecules including proteins, lipids, lipoproteins and DNA. These free radicals are naturally scavenged by antioxidant mechanism in mammalians. Uncontrolled generation of free radicals is associated with lipid and protein peroxidation, resulting in cell structural damage, tissue injury, or gene mutation and ultimately leading to a variety of pathophysiological disorders such as arthritis, diabetes, inflammation, cancer and genotoxicity (Kourounakis et al., 1999; Gulcin et al., 2002a). …show more content…
In certain circumstances, the body's natural defence mechanism becomes inefficient, which makes mandatory dietary intake of antioxidant compounds as an alternative, suggesting that there is an inverse relationship between dietary intake of antioxidants and the incidence of diseases caused by the deficiency of these substances. The commercially available synthetic antioxidants are used to reduce the deleterious effect of oxidative-induced reactions in food and biological systems. However, the potential toxicity of these synthetic antioxidants has aroused an increased interest in identifying alternative natural and safe sources of antioxidants, and the search for natural antioxidants, especially of marine origin, has notably increased in recent
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247 Words | 1 PagesAn enzyme can not be considered a reactant because, like catalysts, the enzyme is never used up in the reaction and is reused again in another chemical reaction. In this lab, the source of hydrogen peroxidase was the potato solution. The substrate that the hydrogen peroxidase acts upon is the hydrogen peroxide.
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Zebrafish
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Can Bacteria Control Bioluminescence Using Quorum Sensing?
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Skin Aging Essay
998 Words | 4 PagesIntrinsic factors and extrinsic factors, both contribute to this process. As discussed earlier, UV-induced damage to the DNA causes a poor renewal of the skin. When exposed to harsh sunlight, an individual is also exposed to the UV light that comes along with it. Excessive exposure can cause premature aging in certain individuals and also is observed as severe pigmentation and sunburns as well. The antioxidants, namely vitamin E and vitamin C are majorly targeted by the UV light and thus, reduce the antioxidant capacity of the epidermis on prolonged exposure.
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192 Words | 1 PagesOver time, more advanced research provided us with a clearer understanding about the mechanism of this non communicable yet morbid disease. Atherosclerosis is detrimental because it affects the blood cells themselves, blood vessel lining, and overall circulatory system. Normally, it is crucial to maintain homeostasis in order to keep the circulatory system functioning efficiently. However, when homeostatic imbalance occurs, injury to the endothelium will result which is the first step to atherogenesis. Examples of imbalance leading to structural vascular changes include hypertension, hyperlipidemia or hyperglycemia.
Radiation Induced Inflammation
857 Words | 4 Pages1.4 Radiation-induced inflammation Ionising radiation causes liver inflammation and injury, and a significant increase in the number of non-parenchymal liver cells has been reported following irradiation (Geraci and Mariano 1993). It is essential to explore the molecular mechanisms underlying the leukocyte transmigration processes to gain an understanding of the inflammatory disorders associated with RILD. Alcoholic liver disease, viral hepatitis and nonalcoholic steatohepatitis are the most common hepatic disorders that harbour risks of fibrosis and the development of cirrhosis (Fig. 2). These disorders are directly associated with persistent inflammation and the harmful substances that are produced as a consequence of oxidative stress, and
Krill Oil Research Paper
808 Words | 4 PagesA healthy diet rich in anti-oxidant vitamins and minerals, helps to stabilize free radicals, thus helping to prevent diseases like cancer. The very food (Processed Commercial Dog Food} your feeding your dog, the food vet clinics and dog food companies promote as being nutritious, is the very thing that is producing-
Parkinson's Disease Research Paper
782 Words | 4 PagesOur recent studies have shown that inflammatory cytokine TNF induces reactive oxygen species via NADPH oxidase that causes oxidation of phospholipids to phospholipid hydroperoxide and Azelaoyl phosphotidadyl choline (Scheme 1) and increases Platelet-activating Factor (PAF) in non-neuronal cells, and I expect brain and nervous tissues are also very susceptible to oxidation due to their high level of polyunsaturated fatty acids and intense consumption of oxygen. Furthermore, TNFα receptor 1 is highly expressed on dopaminergic neurons, and their expression increases in PD (). More significantly, Oxidatively truncated phospholipids are internalized, migrate to mitochondria, and then disrupt mitochondrial function, in a way aided by Bid, to initiate intrinsic apoptosis (23, 24). PAF and oxidatively truncated phospholipids, a proinflammatory lipid mediators bind to the G-protein coupled transmembrane receptor, the
Persuasive Essay: Why Chocolate Is Bad For Our Health
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Mediterranean Diet Research Paper
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Free Radical Inorganics
936 Words | 4 PagesFree radicals, acknowledged in chemistry since the birth of the 20th century, were originally used to describe common compounds in organic and inorganic chemistry, and several chemical definitions for them were suggested. Only in 1954 when the pioneering work of Daniel Gilbert and Rebecca Gersham was published (Gilbert DL (ed.), 1981) were these radicals proposed as important players in biological environments and responsible for destructive processes in the cell. After which, in 1956, Herman Denham (Harman D, 1956) suggested that these species might play an important role in physiological events especially in the aging process (Harman D, 1981). His hypothesis, the free-radical theory of aging, inspired various studies and research efforts
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