Epigenetic Synthesis

DNA is a double-stranded helix composed of a phosphate backbone and deoxyribose, and encodes information by the sequence of its nucleotide bases, which are composed of adenine, thiamine, guanine and cytosine. DNA undergoes transcription, which produces single-stranded mRNA, which uses uracil in place of thiamine. Next step is translation, in which the RNA becomes a protein, which then can act as structural units or enzymes.

Abraham Lincoln was shown to have a tall/thin build, a long face, and enormous hands and feet. He shares the same symptoms of an individual suffering from Marfan syndrome. Marfan syndrome is a genetic disease that affects the connective-tissue of an individual. The connective tissues help the human body grow and develop by holding cells, organs, and tissues together. This disease is caused by mutations in a gene called “FBN1”. This gene holds the information to make a protein known as “fibrillin-1”. This protein is responsible for repairing tissues and controlling the growth throughout the body. The FBN1 gene is responsible for this mutation. This gene can reduce the amount of healthy fibrillin-1 proteins, thus resulting in instable tissues

SRT1720 is a selective activator of SIRT1. Previous in vitro and in vivo studies using various cancer cell models show the role of SIRT1 either as an oncogene or a tumour suppressor gene. The oncogenic potential of SIRT1 is exemplified by studies indicating that blockade of SIRT1, like other HDACs, triggers growth arrest and apoptosis in breast, colon and lung cancers.

Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is an excellent target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation.

Ataxia Telangiectasia (A-T) is an inherited disorder that affects the nervous system, immune system, and other systems of the body. The disorder usually progresses before the age of 5 and it makes it difficult for coordination and causes delayed development of motor skills like walking, problems with balancing, and using your hands to grab items etc. A person may even have slurred speech, sway when they walk and wobble. These problems can affect a person as they get older and the effects can become worse as the person ages. Effects vary with each patient some may have severe immunodeficiency in which they cannot produce antibodies to fight off disease.

Epigenetics influences our genes in many ways, some positive well others are negative.The debate “nature vs. nurture” is put to the test through twins, both twins have the same DNA, so why is it one twin could have asthma. Most of the differences between twins is Epigenetics. First off, epigenetics refers to heritable changes in gene expression that does not involve changes to the DNA sequence. Change is a natural and somewhat regular occurrence but can also be influenced by several factors. Some factors include age, lifestyle and disease. Epigenetics commonly manifest in several areas. These areas include skin cells, liver cells as well as brain cells, where some effects result in cancer. The field of epigenetics is quickly growing and with

Telomerase Telomerase is a specialised ribonucleoprotein reverse transcriptase enzyme[1]. It carries its own RNA molecule. Telomerase is functional at the tips of chromosomes in areas known as telomeres. The main function of telomerase is to extend the 3' ends of DNA strands by adding 'TTAGGG' repeat sequences as it is

Genes can recognize mistakes during cell division. These mistakes are called mutations. Humans are not always born with mutations, they can occur during the whole life when natural processes in the cell take place. Mutations also happen because of tobacco, radiation, ultraviolet radiation, substances in food, and chemicals in the

There are four main perspectives in psychology. These are known as; biological perspective, learning perspective, cognitive perspective, and sociocultural perspective. Each perspective aids in the understanding of human behavior. However, not one perspective can explain all of human behaviors. This is due to each perspective playing different roles in ones behavior. To fully understand human behaviors scientist must understand the four perspectives.

Abstract: Cancer is considered one of the leading causes of death in the United States. Although preventative strategies, early detection, and improved treatment options have been developed since its origin, novel targets and therapeutics are still needed. Since concluding that cancer is mediated by genetic and epigenetic alterations of the cell, many research groups are now focusing on other means of prevention and therapy via nutrition, epigenetic mechanisms, and non-coding RNAs which have been shown to control gene expression and have many different functions at the cellular level. With the advent of high-throughput sequencing in human cancer, the potential to identify novel biomarkers and potential targets of disease has increased tremendously

Genetic information is found in each part of our cell. Chromosomes contain many genes, a section of DNA. These genes have a coding system using adenine, thymine, cytosine, and guanine, which are strung together in a long chain to create a unique DNA sequence. Different genes control the development of special characteristics of an organism. With genetic testing, a person can see their specific genetic code. By looking at the specific sequence of genes or chromosomes, certain genetic or chromosomal conditions can be identified or ruled out. For example, looking at genetic code can show if you have the genetic makeup to eventually develop Alzheimer’s. This does not mean you are going to develop Alzheimer’s, it just means

Cancer, heart disease, blood disorders, nerve disorders, and many more genetic diseases are affecting millions of people around the world. The more society advances, the more degenerate diseases are affecting the citizens. For a number of years researchers have been searching for cures. With new developments in gene editing, treatments for many diseases are just around the corner. Gene editing with new technology, CRISPR, matches with a specific gene and splits the protein. The researchers then combine the broken gene with a healthy gene. This new healthy gene is now modified and free from the mutation it had before. Although many individuals’ ethics and morals stand in the way of gene editing, this technology affects society in many different

Mendel 's laws of genetic inheritance initiated an era of genetics which feeds on the complete functional information of each and every ' 'modern ' ' gene of the organisms.

Genetic modification is a unique set of genes technology that affect the genetic system of the living organisms such as : animals ,plants and micro organisms.

DNA has a massive job of keeping you alive. In essence, a microscopic strand of genes support your entire body and life. There are many smaller jobs protein has to accomplish that combine to accomplish the main job of supporting life. To start, DNA codes for proteins and every protein provide an essential biological function. Also, cells make up tissues, organs, and body systems. Body systems interact with each other to maintain homeostasis.