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Coffee Research Paper

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7. Discussion
Findings from numerous studies indicate that coffee is considered as an important dietary factor related to elevation of adiponectin level. Coffee may also reduce the concentration of leptin; however, it is still under debate.
Coffee is considered as one of the food sources containing several antioxidants [49]. According to studies, dietary intakes play the key role on prevention or promotion of inflammation and obesity [50-53]. Beside dietary intakes, coffee may increase insulin sensitivity via the reduction of inflammation [54]. In addition, lower levels of adiponectin induce greater risks of inflammation and insulin resistance. It is possible that coffee reduce low grade inflammation mediated through the elevation of adiponectin. …show more content…

Evidence indicated that KLF7 inhibit the adiponectin, leptin and PPARγ [6]. Furthermore, over expression of KLF7 suppress catechin-stimulated adiponectin expression. Consumption of green tea via its catechin attenuates the expression of KLF7 and enhances PPARγ and adiponectin expression and secretion [6]. Green tea enhances energy expenditure. It is also play the important roles on increase the sympathetic nervous system and elevate thermogenesis via the stimulating the norepinephrin secretion. Green tea and catechin display the key role on fatty acid oxidation and weight loss [5, 61, 62]. Adiponectin involves in fatty acid and glucose metabolism as well as insulin sensitivity and weight loss [63]. It is possible that green tea consumption beneficially affect metabolic pathways via increase in adiponectin …show more content…

Regarding coffee and adipokines, there is no cohort study. Cross sectional studies have reported positive roles of coffee on adiponectin concentration [3, 7]. It is possible that coffee have diverse effects in different population [60]. In addition, the amount of coffee consumption which can improve levels of adiponectin is not clearly confirmed. The potential mechanism in this regard is also debated. It is affect adiponectin or it has favorable impact via the weight loss and improvement of metabolic effects.
To our knowledge there is one study regarding the green tea and leptin. More studies should be conducted regarding green tea, leptin and adiponectin. However, green tea may involve in the changes of adiponectin concentration through weight loss [5].
In conclusion, fewer studies are conducted about the possible role of green tea and coffee with concentration of leptin. Based on several studies coffee involve to increase the levels of adiponectin by the unknown mechanisms. Green tea because of its catechin and other components may beneficially influence on circulation of adiponectin. However, more investigation should be conducted in

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