Guyabano Essay

Guyabano (Annona muricata Linn) which belongs to the family of Annonaceae is an evergreen tree species utilized as traditional medicines. Extracts and metabolites from this plant show pharmacological properties such as anti-inflammatory, antibacterial, anthelmintic, antiulcer, and free radical scavenging activity. Beside medicinal uses, this plant has high economic value due to its nutritive and edible fruit, bark, leaves and provides substantial livelihood support to local inhabitants. A wide range of chemical compounds including Alkaloids (acetogenins), isoquinoline, lipids, Annomuricatina (protein), lactones, Bullatacin, Muricoreacinetc. have been detached from this species. The present review summarizes the information concerning the traditional

Traditionally, scientists have explained acne as a buildup up dead skin cells in the follicles of the sebaceous glands, which excrete an oily skin and hair lubricant. The commonness of the problem in adolescents was thought to be fueled primarily by changes in levels of sex hormones.

But new research has shown that acne is much more complex than previously believed. Where older sources categorized acne as either inflammatory (large, red, pus-filled pimples) or non-inflammatory (whiteheads and blackheads), studies have shown that inflammation is actually a key to the process that produces all pimples and acne. In fact, inflammation-producing immune cells surround all acne-affected hair follicles significantly before any pimple becomes visible.

Research has also shown that acne is caused, in part, by an exaggerated response from the innate immune system to the presence of the bacteria Proprionibacterium acnes. This appears to be an overly zealous response by a part of the immune system designed to protect the skin from being penetrated by bacteria. This idea was supported by a recent paper in the Journal of Investigative Dermatology, which found that sebaceous glands also express an inflammatory immune compound. (David Gutierrez,