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Haloothane Research Paper

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MINISTRY OF HEALTHCARE OF RUSSIAN FEDERATION INSTRUCTIONS for the application of the drug for medical use HALOTHANE name of the drug Registration number: Tradename: Halothane. International nonproprietary name: Halothane. Dosage form: inhalation liquid. Composition: One vial contains - Active substance: 99.99% halothane (vol / vol) excipient: thymol 0.01% (vol / vol) Description: Clear, colorless, mobile, heavy liquid having characteristic odor. Pharmaco-therapeutic group: Remedy for inhalation for general anesthesia. Code: АТХ: N01АВ01 Pharmacological properties Pharmacodynamics: Halothane is a drug for inhalation anesthesia from the group of fluorinated aliphatic compounds. Causes the rapid introduction in anesthesia without \or with a minimal …show more content…

Proper dose is achieved using of the calibrating evaporator, arranged outside of the closed circulation system (to prevent overdosing). Adults Induction. For anesthesia induction with a flow rate: 8 l / min, start with Halothane at a concentration of 0.5. % (With oxygen), then gradually increase the concentration of Halothane vapor in a mixture to about 0.5-3. %. Usually about 0.5-1.5% are enough for adults as the supporting concentration. Children The concentration of 1.5-2.0 vol. % is used for children during the induction. Aged Elderly patients require lower dosages of halothane, but the actual dose is based on the physical condition of the patient. Surgical stage of anesthesia is usually achieved after 4-6 minutes. The minimum alveolar concentration (MAC) for adults with a mixture with oxygen is about 0.77. % In mixture with nitrous oxide is about 0.3. %. Halothane MAC in a mixture with oxygen for children up to 6 months is about 1.08. %; 10 years - about 0.92. %; for persons over 70 years - about 0.64. %. At the end of the operation increase the flow of oxygen for more rapid elimination of the drug and to eliminate possible

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