Introduction: Piriformis syndrome (PS) is a neuromuscular condition with a special combination of several characteristic manifestations mainly highlighted by gluteal pain(1). Others may involve pain in the lower back area down to buttocks, paraesthesia, numbness and limitations to some weight-bearing activities like walking for long periods, standing and sitting to some degrees(1-5). Other symptoms may also include: the sciatic notch tenderness, swelling, sexual dysfunctions and splayfoot with a dominant external rotation in supine lying indicating tightness of the muscle(6). In general, four primary manifestations had the highest tendency to be found as was reported by a recent systematic review. These include: posterior buttock pain, increased sciatica symptoms with sitting, tenderness over the greater sciatic notch and positive results of Piriformis muscle tension tests
(1) And secondly in unilateral Asterixis, caused by specific lesions in brain regions. Hyperreflexia is an exaggerated and overactive deep tendon reflex to a stimuli, processed by the involuntary nervous system. This involves the upper motor neuron and is usually resulting from spinal cord injury or metabolic disease. This reaction can include: change in heart rate, excessive sweating and high blood pressure. (2) The young patient is brought to the emergency room with acute mental status and stroke-like symptoms.
Various laboratory tests can then be carried out to confirm the diagnosis. Thyroid-stimulating hormone (TSH) test is the most sensitive test to evaluate thyroid function and is usually the first test performed. TSH is a pituitary hormone that regulates the production of two hormones: thyroxine (T4) and triiodothyronine (T3). T4 and T3 test is another blood test used to diagnose Grave’s disease. Generally, low levels of TSH and elevated levels of T4 and T3 indicate Graves’s disease.
This can be very life threatening and may seriously damage the heart muscle. There are different types of biomedical tests to find out the diagnosis of myocardial infarction. One of which is blood tests to check for heart muscle cell damage, this is usually done using a high sensitivity troponin which is a cardiac and skeletal muscle protein that is used in the laboratory diagnosis of heart attack. They are classed as cardiac markers; troponin I and Troponin T, however they are both sensitive and specific indicators of damage to the heart muscle known as myocardium, they may be measured in the blood to differentiate between unstable angina and heart attack in people with chest pain or acute coronary syndrome. An example a person who may have experienced a myocardial infarction freshly would have an area of damaged heart muscle and raised cardiac troponin levels in the blood.
Its most important clinical application involves the detection of bacterial infection. This can be tested by simply mixing the serum of suspected individual which contain the antibodies with the antigens of specific bacteria the accumulation of clumps confirms the presence of particular bacterial infection.  This test can be performed in various ways including slide agglutination reaction, tube agglutination reaction, indirect agglutination inhibition reactions etc. Another important practical application involves blood group test of
First, the clinical evaluation which is based on doctor's questions and the external investigation. The second step is the blood test that is used to measure levels of TSH,TT4, andT3 hormones which are secreted from the thyroid gland. Finally, the radioactive iodine uptake test that is based on measuring the iodine absorbing by the thyroid gland. Thus, in order to prevent the development of thyroid disorders to critical conditions, it is essential for people to periodically see a doctor because the early detection of thyroid disorders improve the overall cure
Laboratory testing is a very essential part of the clinical decision making process. The test result strongly influence medical diagnosis as well as the therapy applied (Lippi, 2006).Hematological results are often influenced by number of pre-analytical variables,these include the anticoagulants used, methods of analysis, the storage temperature and the time between when the samples were taken and when they were analyzed (Gulatietal., 2002).Delayed sample analysis could result in hematological changes in the measured parameter, which could complicate the interpretation of the resulting data (Lippi et al., 2005). Whole blood is usually treated with anticoagulants to prevent them from clotting. Ethylenediamine tetraacetic acid (EDTA)salt sodium
Introduction: Screening tests are group of tests that help identify people with increased risk for a conditions or disease before they have symptoms or even realize they may be at risk so that preventive measures can be taken .Screening tests help detect disease in earliest stage . Newborns screening tests is a public health activity aimed at early identification of newborn affected with certain genetic or metabolic conditions. Early diagnosis and treatment of these conditions has been shown in many cases to reduce morbidity, premature death , mental retardation , and developmental disabilities History: Newborn screening programs in the US began with the work of Dr. Robert Guthrie, who in the 1960's developed a screening test for phenylketonuria.