Hypothyroidism Research Paper

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ABSTRACT

Introduction: The aim of the study is to find the antioxidant status in hypothyroidism. Hypothyroidism otherwise known as under active thyroid. It takes place when the thyroid gland doesn’t produce enough thyroid hormone for the body need. It is the most common thyroid disorder. It occurs mostly in women and increase with age

Material and Methods: 40 subjects were divided into two groups of normal healthy individual ( 20 in numbers ) as Group I and hypothyroidism patients ( 20 in numbers) as Group l l from dental outpatient department of Saveetha Dental College and Hospitals. Blood samples were collected from the participants and it was distributed in plain collection tube and centrifuged in 2500 rpm for 10 minutes. The Serum was
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Conclusion: Our study revealed that there is an imbalance of antioxidant status in women with PCOS. Increased oxidative stress and decreased antioxidant capacity may contribute to the increased risk of CVD in women with Hypothyroidism. Further research on oxidative stress in hypothyroidism is needed.

Keywords: Hyperthyroidism, Antioxidants, endocrine, metabolic disorders, endocrinopathy, Malanaldehyde, Superoxide dismutase, Pyrogallol Autoxidation
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This leads to lipid peroxidation and oxidative DNA loss but can interfere with physiology and intracellular signal transduction. The resulting change in intracellular redox status leads to the activation of protein kinase, for example, tyrosine kinase, protein kinase c, and the mario-activated protein kinase cascade leading to modified cellular functions.

Oxidative stress compounds hypothyroidism. Hypothyroidism is a state that increases the oxidative stress. In this study, the biomarker is high in MDA level therapy-innocent primary hypothyroid patients. After treatment with L-thyroxine, the pressure marker is reduced to a considerable degree. MDA can also be used as a useful biomarker to measure and monitor oxidative stress. The role of antichrist in the form of selenium is incomplete (5). In our research we find antioxidant status in hypothyroidism

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