Polymers are additives used widely in pharmaceutical systems for numerous objectives, i.e. as suspending, emulsifying and flocculating agents, adhesives, and for packaging and coating materials. Polymers are made up of repeating monomer units with a high molecular weight. Their chemical reactivity depends on the chemistry of their monomer units, but their properties depend mainly on how the monomers are assembled together. Nearly all polymers exist with a range of molecular weight and for convenience the reported molecular weight of a polymer is the average molecular weight. In agree with Florence & Attwood, 2003 water soluble polymers have the capability to increase the viscosity of solvents at low concentrations, to swell in solutions and …show more content…
The kinetics of the gel layer formation depends on the external parameters like temperature, molecular weight of the polymer, and pH of the solution. HPMC was the subject of many studies. The Ph. Eur. describes hypromellos, as a partly O-methylated and O-(2-hydroxypropylated) cellulose. It is available in several grades that vary in viscosity and extent of substitution. Grades may be distinguished by appending a number indicative of the apparent viscosity, inmPas, of a 2% w/w aqueous solution at 20°C. Hypromellose defined in the USP 32 specifies the substitution type by appending a four-digit number to the nonproprietary name: e.g. hypromellose 1828. The first two digits refer to the approximate percentage content of the methoxy group (OCH3).These two digits refer to the approximate percentage content of the hydroxypropoxy group (OCH2CH(OH)CH3), calculated on a dried basis. It contains methoxy and hydroxypropoxy groups conforming to the limits for the various types of hypromellose. Molecular weight is approximately 10000–1500000. Hypromellose (INN), short for hydroxypropyl methylcellulose (HPMC), is a semisynthetic, inert, viscoelastic polymer used as excipient in eye drops, as well as an excipient and controlled-delivery component in oral medicaments, found in a variety of …show more content…
Evidence suggests that the chemistry of hypromellose encourages a strong, tight gel formation compared to other cellulose derivates. As a result, drug-release rates have been sustained longer with hypromellose than with equivalent levels of methylcellulose (MC), hydroxyethylcellulose (HEC), hydroxypropylcellulose (HPC) or carboxymethylcellulose (CMC). For these reasons, hypromellose is very often the polymer of choice over other cellulose
Javier “Chicharito” Hernández was born on June 1, 1988 in Guadalajara, Mexico, to Silvia Balcazar and Javier Hernández. He was inspired to play soccer because he was born into a family where both his father and grandfather were professional soccer players. Chicharito is currently not married and still playing soccer. When Chicharito was 9 years old he began his career of soccer at the C.D. Guadalajara Youth Soccer Academy. At the academy, young Chicharito played against youth soccer teams and proved to be exceptional at it.
On October 3, 1974, at around 10:45 pm, Elton Hymon and Leslie Wright of the Memphis Police Department were responding to a “prowler on the inside” call. They made the scene and observed a woman in the house next to the intended home of the call. She was standing on her front porch pointing at the house. She advised that she had heard glass breaking and someone was breaking into the house next door. As Wright showed both officers on the scene on his radio to dispatch, Hymon went to the rear of the house.
Delano comes across a beaten up ship, ripped sails, seems to be moving on its own. The ship may have been through a storm b/c of torn sails, acts like a ghost ship. Very interested in ship and also inquisitive about saying in spanish imprinted on the ship, which translates to “follow your leader”. Foreshadows upcoming events about wanting to figure out the secrecy about the ship.
1. Where does your alien live? Include the name of your planet and a description. My alien lives on Jupitoris.
Loreta Velazquez was born in Havana, Cuba on June 26th, 1842. She has a Spanish father and a French-American mother. In 1849, she was shipped from Cuba to New Orleans to live her aunt, she attended Catholic school. There she learned to speak English and eventually married an army officer known as William, she ran away with him and at the age of fourteen.
Before the English venture of Roanoke, many Europeans had tested the waters of the New World. Whether it was to raid ships along the coast of the Newfoundland or establish colonies in the New World, several men had plans for exploration. Elizabeth’s sea dogs were prompted to partake in piracy and attack the Spanish at sea. However, due to various dangers with Spanish warships and the Bahama Channel the privateers were not consistently successful (Horn 35). Ralegh recruited the “most remarkable men” for his All-Star exploration team.
Swish, that was the sound of Hayden Hoose, he just made a three point shot and swished it. Hayden Hoose is the youngest male kid to make a half court shot in a basketball game. He was considered a basketball legend; people from China were hearing about Hayden Hoose. Hayden not only plays basketball he also plays baseball. People from China not only heard about his perfection for basketball, they also heard about his perfection for baseball.
A man who worked at his family’s company his whole life , has a pretty interesting story to tell about when he got drafted in 1933 . His name is Daniel Capozello. Before he entered the military he had 4 years of a high school education (High school Diploma). First he had to go through a 12 week basic training camp (boot camp).
Hamsterdam is an unofficial legalized drug zone in Baltimore. It emerges out of the need to lower crime rate in Baltimore. Bunny Covin starts out as a Major who does not care anymore because of his nearing retirement. However, the condition of the city makes him feel like a failure, so he decides to make an impact when he has the chance. While all the police are all busy doing street rips, there is no time or people left to do real police work.
Better With Time: Nas Celebrates Hennessy 's 250th Anniversary Nas attends Hennessy 's 250th Anniversary celebration at the Lincoln Center 's Alice Tully Hall in New York City. Hennessy recently celebrated 250 years of excellence with a star-studded event at the Lincoln Center 's Alice Tully Hall in New York City. Amongst those present at the celebration, was Nas, the Hennessy ambassador shared his excitement for the brand stating, “We all hope we can last for 250 years in terms of our name, history, and brand. I am nowhere near that,” he said.
Wally Schirra a humorous character. One of his mottos of life is," we should resort to jokes, pranks and good natured kidding to relieve tension, stress and boredom." This motto in his life is something I admire in people. The drive of a person who can keep a smile on their face, no matter the situation. Wally Schirra also had a house in Kauai, so he must have appreciated the beauty of our islands.
Larry Hiibel was arrested and convicted in Nevada state court for failing to identify himself to a police officer who was investigating an assault. Some states including Nevada, has a law that requires a person to tell an officer his name if asked. Larry Hiibel challenged the conviction, claiming it violated his Fourth and Fifth Amendments, the right not to incriminate himself and to be free from unreasonable searches. The state intermediate court and Supreme Court rejected his argument in affirming the conviction. At first when I read this I think that this arrest and conviction violated Larry Hiibel Fourth and Fifth Amendment because he was arrested for the action of remaining silent but in a 5-to-4 opinion written by Justice Anthony Kennedy,
Who is Benjamin Jealous? Benjamin Jealous was the NAACP leader from 2008 until 2013. Ben also was the youngest NAACP leader in history and under his leadership, NAACP grew into the largest civil rights group in the US. Before Jealous was the leader of NAACP, he was a journalist for 15 years, and had a passion to fight for people’s rights.
Bernal Diaz was a conquistador who joined Cortés on his missions of the conquest of New Spain. Hernan Cortés was the leader responsible for conquering the Aztec Empire in Tenochtitlan. Hernan was a part of an expedition funded by the king of Spain to spread Christianity and to acquire wealth from various places in the Americas (mainly island countries). Cortés heard of the rumored wealth of Mexico. Cortés and a group of men disobeyed orders to stay in Cuba, and made their way to Mexico.
I grew up in Bloomfield, PA, a small city-like neighborhood about three miles away from downtown Pittsburgh. The community consists of a series of uniform type “row” houses, most backyards include a small grassy area with a fence that is shared by the neighboring house, and the alleyway in between is where the majority of our childhood games were played. Bloomfield is sometimes referred to as Pittsburgh 's Little Italy because of its historically Italian-American population. My neighborhood is full of kids, generations of Italian families, and the delicious scent of fresh bread baking from Sanchioli Brothers Bakery just a couple blocks away. The main road, Liberty Avenue, is complete with an array of Italian restaurants, novelty shops, bakeries,