Immunological Malfunction Case Study Answers

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Elizabeth Barron Winters OA April 17, 2017 Case study 2 Immunological malfunction Question 1 IgA is a monomer in plasma and is a dimer in mucus, tears, intestinal secretions and milk. Its function is to prevent pathogens from penetrating underlying tissues and sticking to epithelia. IgD is a transmembrane protein of B cells and its function is to help the activation of B Cells by antigens. IgE is a transmembrane protein of basophils and mast cells, its function is to simulate the release of histamine and other inflammation mediators. IgG is the circulating antibodies in blood plasma, it is secreted in the secondary immune response. It is also able to cross the placenta and give temporary immunity to the fetus. IgM is also the circulating…show more content…
Question 14 HLA is a major histocompatibility complex a family gene on chromosome 6; a protein in most cells in the body. A matched sibling is the best possible donor because it decreases the chances of your body to reject the transplant. Since a sibling inherits some of the HLA markers from the parents its an easier match and more successful; sometimes siblings and parents are a match which then you 'd try and test an unrelated donor to see if that will be compatible. Question 15 Prenatal testing is a test done to a see if the fetus/ embryo will have any possible birth defects, or health problems by testing amniotic fluid or placental cells. This can also be done to know possible gender, select preferred traits, test for family genetics. Question 16 Susan and Joe would be able to select a child with matching HLA if they did a preimplantation method were an embryo would be fertilized and at the 8 week mark, test it for any defects and look for the preferred traits and HLA that would match Daniels and then implant it in Susan 's uterus for the embryo to

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