Between June 1980 and March 1981, Hospital for Sick Children found several newborn infants dead. At first, officials believed the incident was just an unfortunate coincidence as at the time it was not incredibly uncommon for multiple people to pass away within a 10 month period. At a later date, an autopsy of a newly passed baby revealed an unusually large amount of digoxin. Digoxin is a drug used to regulate a hearts beating pattern. Shortly after another infant had also died from an increased amount of digoxin.
Patient Case Patient: Angelique van Eeden Hospital number: GP 6317 1693 Date of birth: 02/06/1981 Main complaint 33 year old female patient presents with a 3 year history of tachycardia; tremors and profuse sweating. Patient also complains of protruding eyes. Previously diagnosed with Grave’s disease in 2013. Received ablation therapy in 2013 but symptoms persist as well as large goitre. Previous symptoms now improving, but patient complains of obstructive symptoms including difficulty swallowing.
Laboratory testing for known causes of brain calcifications came back negative; thus the patient was diagnosed with Fahr’s disease, a condition that was diagnosed in her younger sibling two years previously. As there is no cure for the condition, the patient received physiotherapy, speech and language therapy, and her diabetic control was optimised prior to discharge from hospital; she made mild improvement in her symptoms. Fahr’s disease is a condition characterised by an idiopathic bilateral basal ganglia calcification. It is a rare disease with prevelance believed to be less than one in a million; most often an autosomal dominant in nature. It can
October 2003, my family was stuck with tragedy. Chloe my little sister started to become ill, she started out with acute symptoms such as pyrexia, rash, hemiplegia, and arthralgia. After two trips to her Primary Care Physician they just continued to claim she had the flu. After a month of her symptoms developing and becoming worse a trip to Miner Medical Center was the only answer. Only being there for about an hour she was transported via life flight to Children’s Hospital in Pittsburg.
Pregnancy can trigger the disease due to women of childbearing years being more at risk of having Lupus. Researchers believe that estrogen plays a role in disease development, but the actual cause of the disease unknown. Environmental factors play a role in the disease such as; exposure to the sun, stress, and smoking can spark an outbreak. Some of the symptoms associated with Lupus are; butterfly shaped rash on the face, feeling severely fatigue, extreme weight
Carter formed her hypothesis that manipulating ApoE in the brain can lead to Aβ clearance and may slow the progression of AD and possibly cure the disease. With the knowledge that nuclear receptors liver X receptor (LXR) and retinoid X receptor (RXR) regulate ApoE expression, Dr. Carter investigated Bexarotene, an RXR agonist. Her research showed that administering Bexarotene to AD mice improved previously impaired memory, cognitive functions, and social behaviors. By choosing to investigate a drug already approved by the FDA for treatment of lymphoma, Dr. Carter proved her efficiency in the field; approval for a new drug would have been much more difficult to obtain when she moved to clinical
After 2 hours of driving, we arrived to the hospital, the doctors told us that she has suffered from severe dehydration and as a results her kidney failed and she might need to be on a dialysis machine. My eyes were filled with tears to know that the absence of the basic medical services in the village was going
Nursing burnout is the major cause of patients that have died from acquiring infection during hospital stay. The risk factors of burnout lead to cognitive detachment in nurses, resulting failure to perform adequate hand hygiene and other infection preventive measures. The study presented that for every 10% increase in nursing burnout, the rate of catheter associated urinary tract infections increased one per 1,000 patients, and surgical site infections increased more than two per 1,000 patients every year. Over 1/3 of the nurses surveyed, estimate that reducing the burnout rate of 10% would prevent over 4,000 infections per year, and also eliminate the associated monetary cost of these infections. (Dr. Cimiotti,
Not being pregnant, I was sick and I barely could get out of bed. This put such a strain on my marriage we divorced. I had four children under the ages of ten to support and raise. My youngest was not in school yet and I went to college. I became very ill and was put into the hospital.
Molly started chemotherapy to destroy her bone marrow and received a transfusion of the cord blood cells a month later. The transplant cured Molly's bone marrow failure, but she still suffers from Fanconi anaemia and visits the doctors 35-40 times a year to screen for solid-tumour cancers. A common cold could have dire consequences for her, but her bone marrow is functioning normally. This was the first case where saviour sibling was used to cure the already existing
If an individual is regularly seen by a health care practitioner the NPC1 gene mutation can be detected early on. Roughly 1 in every 120,000 live birth that will be affected by this gene(3). Children between the ages of 5-15 die and the progression of the symptoms relating to the gene in adults is usually slow(2).
Grace is a 78-year-old female who is diagnosed with malignant neoplasm of pancreatic duct (C25.3). Grace was previously treated with surgical resection of the distal pancreatectomy, cholecystectomy, splenectomy, and low anterior resection with colorectal ostomy, gemzar, abraxane, cisplatin, opdivo, abemaciclib, galunisertib, but still experienced disease progression. Pathology demonstrates T2, N1, M1 disease with 9 out of 27 lymph nodes remarkable with metastasis to the colon. Your denial indicates that Zejula is not approved for her diagnosis. Zejula therapy is a poly (ADP-ribose) polymerase (PARP) inhibitor indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal
Epithelioid Hemangioendothelioma affects about 0.1 percent of the American population with an overall 5-year survival rate of 55% after a standard primary radical treatment. 1,2 Crazy sexy cancer is a documentary about a young lady, age 31, who was diagnosed with epithelioid Hemangioendothelioma, stage IV cancer on Valentine’s day in 2003. One morning, Kris felt sick and decided to see the doctor and that’s when she was diagnosed. Since her cancer was rare, her only treatment options were experimental ones. From the doctor’s report,
Eisenmenger syndrome has decreased due to the prevention of prolonged pulmonary hypertension through early surgical correction of certain congenital defects. Approximately 8 percent of individuals with congenital heart disease will develop Eisenmenger syndrome. Pregnancy can result in cardiovascular changes that may increase the risk of potentially life-threatening complications in a woman with Eisenmenger syndrome as well as the fetus. The treatment of Eisenmenger syndrome is based off of specific symptoms of each patient and can vary. Patients are encouraged to seek help from a cardiologist, Doctors that specializes in the treatment of lung diseases, and a hematologist.
Opioid therapy was used in three patients (14%). The complications observed in this group were a recurrence of the disc herniation after 18 months requiring surgical treatment in one patient, a seroma that resolved spontaneously with complete recovery in one patient, and a dural tear that resolved with conservative treatment prolonging hospital stay to 48 hours in one patient. When comparing Group 1 (OD) with Group 2 (MED), the only statistically significant differences found were for the following variables: the size of the incision, length of hospi- tal stay, operative time, and immediate postoperative pain at the incision. The two former variables were greater in the OD group (P 0.01 and P 0.05, respectively), and the latter two were greater in the MED group (P 0.01 in both) (Tables 1 and 3). The VAS score (Fig.