Lichen Planus Case Study

Background: Lichen planus (LP) is an inflammatory dermatosis with an unknown etiology. Although usually lichen planopilaris (LPP) occurs within terminal hair follicles; there are some reports of concomitant involvement of vellus hairs that present with papular eruption of the face along with frontal fibrosing alopecia (FFA).
Method: Here we report three patients presented with asymptomatic facial papules with histologic examination in consistence with lichen planopilaris.
Result: Based on these cases report isotretinoin can be an effective modality in managing this unusual variant of LPP/FFA.
Conclusion: This study showed a significant response to oral retinoid in all cases.
Limitation: We need large sample size to show isotretinoin is effective on treatment of this form of LPP.

(5) The outstanding feature of this study is the significant response to oral retinoid in all cases.

Material and methods:

CASE 1:
A 30-year-old woman presented with papular eruption on her face that had been started 1.5 years before her visit to our center.
She stated that the asymptomatic papules arose suddenly over several weeks leading to roughness of her face.
She also had experienced a bilateral eyebrow loss since 2 years which made her to undergo a cosmetic tattoo after getting disappointed of several topical treatments all of which failed to an eyebrow growth.
Her medical history revealed no specific disease. Her family and drug history was negative as well.
Physical examination revealed numerous skin colored to yellowish, smooth, 1-2 mm papules symmetrically distributed over the cheeks extending to perioral and mental region. (Fig1a).These papules were confluent and sharply demarcated from normal skin. We recognized a mild frontal hairline recession concomitant with perifollicular erythematous scaly papules. Whereas the examination of other sites of her scalp was completely