Literature Review On Probiotics

1950 Words8 Pages
2. REVIEW OF LITERATURE
2.1 History
The term Probiotics was first time used by two researchers in 1965, and since then it has been redefined and explored further. They described Probiotics as ‘substances secreted by one microorganism that stimulate the growth of another (Lilly and Stillwell,1965).The credit as a discoverer of their role though goes to Eli Metchnikoff, for his original observation of the positive role played by some selected bacteria. He also suggested that “The dependence of the intestinal microbes on the food makes it possible to adopt measures to modify the flora in our bodies and to replace the harmful microbes by useful microbes” (Metchnikoff,1907).In 1989, Fuller redefined Probiotics as “A live microbial feed supplement
…show more content…
Evidences from in many studies suggest that Probiotics have shown enhancement of specific as well as nonspecific immune response (Sanders, 1999). Numerous studies have established that L. acidophilus is able to improve immunity of host by production of strong colonies in the intestinal tract, not allowing pathogenic bacteria to create any destruction in the host body (De Simone et al., 1993; Perdigón et al., 1993). L. acidophilus may also boost up immunity by producing secretor cells of intestine (Cunningham et…show more content…
Pathogenic attack is the major cause of elevated secretions (Casburn-Jones and Farthing,2004; Sherman and Wine,2006).The activity involves their attachment to the mucosal wall, hindering the enterocytes which are involved in absorption phenomenon, altering the intercellular tight junctions by hicking the intestinal permeability and finally releasing enterotoxins like E.coli heat labile toxin. These enterotoxins interfere in the transport of Na –H ions and promote the diffusion of Cl- ions in the small intestine (Janecki 2000, Field

More about Literature Review On Probiotics

Open Document