Literature Review: The First Tracheal Intubation
REVIEW OF LITERATURE The first tracheal intubation was reported in 1543 by Vesalius in an animal . In the early 1870's, Trendelenburg from Germany performed the first endotracheal anesthesia in man. Macewen in 1878 reported the first elective endotracheal intubation for anesthesia.(21) CIRCULATORY RESPONSE DURING LARYNGOSCOPY AND TRACHEAL INTUBATION : The effects of endotracheal intuabation and laryngoscopy producing pressor response causing tachycardia, rise in BP and cardiac arrhythmia were first reported by Reid and Brace(1) in 1940 .They concluded that cardiac reflexes could originate in trachea, larynx , bronchi or lungs & effect a response by sudden increase in vagal tone. These reflexes were termed vasovagal as both afferent …show more content…
Derbyshire et al (2)found that one minute after laryngoscopy and tracheal intubation,mean arterial pressure increase by about 35% and heart rate by 18% over the control levels.These cardiovascular changes are accompanied by elevations in plasma catecholamines: adrenaline increases by 40% and nor-adrenaline by 45%.Sribman et al(27) has divided the pressor response into two …show more content…
It was concluded that dexmedetomidine premedication in a dose of 0.6µg/kg body weight over 10 min blunted the rise in intraocular pressure caused by succinylcholine and intubation and attenuated the haemodynamic response to laryngoscopy and intubation.In 2008, Basar H et al.,(39) conducted a randomized prospective double blind controlled study to investigate the haemodynamic, cardiovascular and recovery effects of dexmedetomidine used as single preanaesthetic dose. Patients were randomly divided into two groups to
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