Liver Donation Case Study

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Introduction Living donor liver transplantation (LDLT) is a lifesaving alternative to deceased donor liver transplantation (DDLT) for patients with end stage liver disease. Best matching between graft size and recipient weight is crucial to avert small for size syndrome and its serious complications. Liver represents approximately 2% of the total body weight and liver graft required to meet metabolic demands should be 40-50% of liver weight which in parallel equals 0.8-1% of the recipient’s weight. This lead to the concept that graft to recipient weight ratio (GRWR) should be at least 0.8% for successful liver transplantation [1-9]. To obtain the desired GRWR of 0.8% or more, accurate estimation of graft weight is required. Whenever left lobe graft meets the required GRWR then it will be preferable to use because of easier surgical technique and lower donor morbidity when compared to right lobe hepatectomy.…show more content…
CT-based volumetric data as well as back table actual graft weight were recorded for each donor. Donors with missed volumetric and/or actual graft weight data were excluded. CT-based liver volume assessment was achieved by scanning the studied populations at 5-mm intervals using the 20-slice multidetector CT (Somatom Definition AS, Siemens, Germany). Liver outlinings were performed by a single operator well trained to recognize the relevant organ boundaries. Inferior vena cava, extra-parenchymal portal vein and the gall bladder were excluded from the outline. Hepatic veins and intra-parenchymal portal venous system and the fissures that did not open into the abdominal cavity were included in the outlining [22]. Volume was determined in milliliters using the automatic volumetry software of Intellispace Portal (Philips Healthcare, Best, The

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