Measles Research Paper

Contents :

Introduction to measles .

Define what is measles .

Describe the measles virus .

Pathogenesis .

Signs and symptoms .

Treatment .

introduction

Measles is one of the most causing of death among young even in children have a vaccine against the measles the measles is an infectious disease caused by viruses and could be transported by blood and the virus enter the body throw the mucous membranes .

The first person who describes measles is a doctor from paris ,then in 1757 a physician said the the measles is caused by infectious material . During this period no vaccine was discovered so the number of death was huge .

Before the invention of measles vaccine 260000 of people died every year , and the vaccine was discovered during

88 percent of people in relationship with an infected person will get measles, if they were not vaccinated. When an infected person speaks, coughs or sneezes, the virus is travel into the air and enters another person’s body through the nose, mouth or throat. People could be also become sick if they come in contact with the mucus or saliva from an infected person

The measles virus can live on infected surfaces and in the air for up to two hours.

Measles virus

The measles virus is a genus Morbillivirus , paramyxovirus. It is 120–250 nm in diameter, with a core of single-stranded RNA, and is closely related to the rinderpest and canine distemper viruses. Two membrane envelope proteins are important in pathogenesis. They are the fusion protein, which is responsible for fusion of virus and host cell membranes, viral penetration, and hemolysis, and the hem agglutinin protein, which is responsible for adsorption of virus to cells.[21]

Three receptors for the H protein have been identified to date: complement regulatory molecule CD46, the signaling lymphocyte activation molecule (SLAM) and the cell adhesion molecule Nectin-4

Infections associated with starvation[6]

Occurrence

The majority of people who got measles were unvaccinated.

Measles is still common in many parts of the world including some countries in Europe, Asia, the Pacific, and Africa.

Travelers with measles continue to bring the disease into the U.S.

Measles can spread when it reaches a community in the U.S. where groups of people are unvaccinated.

Measles is a human disease. There is no known animal reservoir, and there is no asymptomatic carrier state

transmision

Measles transmission is primarily person to person via large respiratory droplets. Airborne transmission via aerosolized droplet nuclei has been documented in closed areas (e.g., office examination room) for up to 2 hours after a person with measles occupied the